Sickle cell disease is one of the commonest serious inherited diseases in the world, and red
cell transfusion is still one of the few effective treatments for acute and chronic complications …

Sickle cell disease (SCD) is an inherited abnormality of the ß-globin chain, which causes a
spectrum of haemolytic anaemias. Clinical manifestations in SCD include anaemia …

Sickle cell disease (SCD) and β-thalassemia are among the most common inherited
diseases, affecting millions of persons globally. It is estimated that 5–7% of the world's …

Both adult and pediatric patients with sickle cell disease face a higher risk of stroke than the
general population. Given the different underlying pathophysiology predisposing these …

Opinion statement Children with sickle disease are at high risk for ischemic stroke and
transient ischemic attacks, usually secondary to intracranial arteriopathy involving the …

Background and Purpose—Brain imaging abnormalities were reported in up to 44% of
children with sickle cell disease (SCD). The prevalence of neuroimaging abnormalities in …

The desiccation of the Aral Sea represents one of the largest human-made environmental
regional disasters. The salt-and toxin-enriched dried-out basin provides a natural laboratory …

Abstract The American Society for Apheresis (ASFA) conducted a one‐day consensus
conference on red blood cell exchange (RBCx) in sickle cell disease (SCD) during its …

Stroke is a severe clinical manifestation of sickle cell anemia (SCA). Despite the prognostic
relevance of transcranial Doppler (TCD), more accurate tools to assess stroke risk in …

Background Cognitive impairment is a major neurological complication of sickle cell anemia
(SCA) in the United States, but there are limited studies of cognitive impairment in Nigeria …