The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention
S Cambier, M Gouwy, P Proost - Cellular & Molecular Immunology, 2023 - nature.com
Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …
of directional migration and activation of leukocytes. CXCL8 is the most potent human …
Neutrophils as potential therapeutic targets in hepatocellular carcinoma
The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
[PDF][PDF] High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
Superoxide anion chemistry—Its role at the core of the innate immunity
CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2023 - mdpi.com
Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …
triggering of an aberrant host immune response, more so than on direct virus-induced …
Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver
Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Developing an understanding for the donor organ immune cell composition and …
technique. Developing an understanding for the donor organ immune cell composition and …
[图书][B] Wintrobe's clinical hematology
JP Greer, DA Arber, B Glader, AF List, RT Means… - 2013 - books.google.com
With the 13th edition, Wintrobe's Clinical Hematology once again bridges the gap between
the clinical practice of hematology and the basic foundations of science. Broken down into …
the clinical practice of hematology and the basic foundations of science. Broken down into …
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
G Günes Günsel, TM Conlon, A Jeridi, R Kim… - Nature …, 2022 - nature.com
Extravasation of monocytes into tissue and to the site of injury is a fundamental
immunological process, which requires rapid responses via post translational modifications …
immunological process, which requires rapid responses via post translational modifications …
Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles
FA Graca, A Stephan, BA Minden-Birkenmaier… - Nature …, 2023 - nature.com
Skeletal muscle regeneration involves coordinated interactions between different cell types.
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …