[HTML][HTML] Distinct Gut Microbiota and Arachidonic Acid Metabolism in Obesity-Prone and Obesity-Resistant Mice with a High-Fat Diet

H Zhang, S Chen, L Yang, S Zhang, L Qin, H Jiang - Nutrients, 2024 - mdpi.com
An imbalance of energy intake and expenditure is commonly considered as the fundamental
cause of obesity. However, individual variations in susceptibility to obesity do indeed exist in …

[HTML][HTML] Triptolide Administration Alters Immune Responses to Mitigate Insulin Resistance in Obese States

L Grodsky, M Wilson, T Rathinasabapathy… - Biomolecules, 2024 - mdpi.com
Individuals who are overweight or obese are at increased risk of developing prediabetes
and type 2 diabetes, yet the direct molecular mechanisms that connect diabetes to obesity …

[HTML][HTML] Biomarkers of Metabolic Adaptation to High Dietary Fats in a Mouse Model of Obesity Resistance

F Milhem, LM Hamilton, E Skates, M Wilson… - Metabolites, 2024 - mdpi.com
Obesity-resistant (non-responder, NR) phenotypes that exhibit reduced susceptibility to
developing obesity despite being exposed to high dietary fat are crucial in exploring the …

Cancer-Associated Hypercalcemia Signals Through the Hindbrain to cause Anorexia

DY Grinman, FM Takyar, P Dann, M Shanabrough… - bioRxiv, 2024 - biorxiv.org
Hypercalcemia, caused by tumor secretion of parathyroid hormone-related protein (PTHrP),
is associated with anorexia and weight loss. We demonstrate that overexpression of PTHrP …