The exosome journey: from biogenesis to uptake and intracellular signalling

S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Routes and mechanisms of extracellular vesicle uptake

LA Mulcahy, RC Pink, DRF Carter - Journal of extracellular …, 2014 - Taylor & Francis
Extracellular vesicles (EVs) are small vesicles released by donor cells that can be taken up
by recipient cells. Despite their discovery decades ago, it has only recently become …

Inside (sight) of tiny communicator: exosome biogenesis, secretion, and uptake

AS Jadli, N Ballasy, P Edalat, VB Patel - Molecular and cellular …, 2020 - Springer
Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

[HTML][HTML] The multifaceted role of SNARE proteins in membrane fusion

J Han, K Pluhackova, RA Böckmann - Frontiers in physiology, 2017 - frontiersin.org
Membrane fusion is a key process in all living organisms that contributes to a variety of
biological processes including viral infection, cell fertilization, as well as intracellular …

Endosomal escape pathways for delivery of biologicals

AK Varkouhi, M Scholte, G Storm, HJ Haisma - Journal of Controlled …, 2011 - Elsevier
Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in …

How cells fuse

NG Brukman, B Uygur, B Podbilewicz… - Journal of Cell …, 2019 - rupress.org
Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …

Mechanics of membrane fusion

LV Chernomordik, MM Kozlov - Nature structural & molecular biology, 2008 - nature.com
Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …

[HTML][HTML] Membrane fusion

R Jahn, T Lang, TC Südhof - Cell, 2003 - cell.com
Membrane fusion, one of the most fundamental processes in life, occurs when two separate
lipid membranes merge into a single continuous bilayer. Fusion reactions share common …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …