[HTML][HTML] Omega-3 lipid mediators: modulation of the M1/M2 macrophage phenotype and its protective role in chronic liver diseases

LA Videla, R Valenzuela, A Del Campo… - International Journal of …, 2023 - mdpi.com
The complex interplay between dietary factors, inflammation, and macrophage polarization
is pivotal in the pathogenesis and progression of chronic liver diseases (CLDs). Omega-3 …

[HTML][HTML] Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function …

MJ Tolentino, AJ Tolentino, EM Tolentino, A Krishnan… - Pharmaceuticals, 2023 - mdpi.com
Age-related macular degeneration (AMD), a leading cause of visual loss and dysfunction
worldwide, is a disease initiated by genetic polymorphisms that impair the negative …

Commentary on: Safety and feasibility of percutaneous needle tunneling with platelet-rich plasma injections for Peyronie's disease in the outpatient setting: a pilot …

A Şahin, M Gül - International Journal of Impotence Research, 2024 - nature.com
In the article titled 'Safety and Feasibility of Percutaneous Needle Tunneling with Platelet-
Rich Plasma Injections for Peyronie's Disease in the Outpatient Setting: A Pilot Study,'Zugail …

Macrophage fate: to kill or not to kill?

AM Marrufo, AL Flores-Mireles - Infection and Immunity, 2024 - Am Soc Microbiol
Macrophages are dynamic innate immune cells that either reside in tissue, serving as
sentinels, or recruited as monocytes from bone marrow into inflamed and infected tissue. In …

[HTML][HTML] Protective effects of paeonol against cognitive impairment in lung diseases

YC Chen, JH Chen, CF Tsai, CY Wu, CN Chang… - Journal of …, 2024 - Elsevier
Pulmonary inflammation may lead to neuroinflammation resulting in neurological
dysfunction, and it is associated with a variety of acute and chronic lung diseases. Paeonol …

Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics

C Mohanty, CK Singh, JA Daccache, W Damsky… - Journal of Investigative …, 2024 - Elsevier
Granuloma annulare (GA) is an idiopathic condition characterized by granulomatous
inflammation in the skin. Prior studies have suggested that GA develops from various …

Innate and Adaptive Immune Responses in Intestinal Transplant Rejection: Through the Lens of Inflammatory Bowel and Intestinal Graft-Versus-Host Diseases

Y Cui, RG Hackett, J Ascue… - Gastroenterology …, 2024 - gastro.theclinics.com
Intestinal failure (IF) is a dysfunctional condition wherein the gastrointestinal (GI) tract is
unable to fulfill its essential functions of food digestion and absorption. 1 Approximately …

Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway

R Fang, R Zhou, D Ju, M Li, H Wang, L Pan, X Wang… - Phytomedicine, 2024 - Elsevier
Background Myocardial fibrosis is a risk factor that contributes to the increase in the
incidence of cardiovascular disease and death, posing a significant threat to human health …

Systemic inflammation in Aβ1-40-induced Alzheimer's disease model: New translational opportunities

A Nefodova, M Rudyk, R Dovhyi, T Dovbynchuk… - Brain Research, 2024 - Elsevier
Alzheimer disease (AD) is the most frequent cause of dementia, and the most common
neurodegenerative disease, which is characterized by memory impairment, neuronal death …

Targeting Macrophage Polarization in Infectious Diseases: M1/M2 Functional Profiles, Immune Signaling and Microbial Virulence Factors

CD Cerdeira, MRPL Brigagão - Immunological Investigations, 2024 - Taylor & Francis
Introduction: An event of increasing interest during host-pathogen interactions is the
polarization of patrolling/naive monocytes (MOs) into macrophage subsets (MФs) …