[HTML][HTML] Clinical metabolomics: the new metabolic window for inborn errors of metabolism investigations in the post-genomic era

A Tebani, L Abily-Donval, C Afonso, S Marret… - International journal of …, 2016 - mdpi.com
Inborn errors of metabolism (IEM) represent a group of about 500 rare genetic diseases with
an overall estimated incidence of 1/2500. The diversity of metabolic pathways involved …

[HTML][HTML] Microplastics dampen the self-renewal of hematopoietic stem cells by disrupting the gut microbiota-hypoxanthine-Wnt axis

L Jiang, Y Ye, Y Han, Q Wang, H Lu, J Li, W Qian… - Cell Discovery, 2024 - nature.com
Microplastics (MPs) are contaminants ubiquitously found in the global biosphere that enter
the body through inhalation or ingestion, posing significant risks to human health. Recent …

Recent developments in sample-pretreatment techniques for mass spectrometry-based metabolomics

RJ Raterink, PW Lindenburg, RJ Vreeken… - TrAC Trends in …, 2014 - Elsevier
Metabolomics is one of the most rapidly evolving of the omics sciences. For phenotyping
individuals, it offers a promising platform that is needed for breakthroughs in biomedical and …

High-carbohydrate diet altered conversion of metabolites, and deteriorated health in juvenile largemouth bass

L Zhao, L Liao, X Tang, J Liang, Q Liu, W Luo… - Aquaculture, 2022 - Elsevier
To explore the effects of dietary carbohydrate level on nutrients metabolism, largemouth
bass juveniles (initial weight, 4.0±0.2 g) were fed three isonitrogenous and isoenergetic …

Selected ion flow tube mass spectrometry for targeted analysis of volatile organic compounds in human breath

I Belluomo, PR Boshier, A Myridakis, B Vadhwana… - Nature …, 2021 - nature.com
The analysis of volatile organic compounds (VOCs) within breath for noninvasive disease
detection and monitoring is an emergent research field that has the potential to reshape …

Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS

P Masson, AC Alves, TMD Ebbels… - Analytical …, 2010 - ACS Publications
A series of six protocols were evaluated for UPLC-MS based untargeted metabolic profiling
of liver extracts in terms of reproducibility and number of metabolite features obtained. These …

Exploration of the serum metabolite signature in patients with rheumatoid arthritis using gas chromatography–mass spectrometry

J Zhou, J Chen, C Hu, Z Xie, H Li, S Wei… - … of pharmaceutical and …, 2016 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease with complicated pathogeny.
There could be obvious alterations of metabolism in the patients with RA and the discovery …

[HTML][HTML] Effects of Clostridium butyricum on growth performance, metabonomics and intestinal microbial differences of weaned piglets

J Liang, S Kou, C Chen, SHA Raza, S Wang, X Ma… - BMC microbiology, 2021 - Springer
Background Weaning stress of piglets causes a huge economic loss to the pig industry.
Balance and stability of the intestinal microenvironment is an effective way to reduce the …

Basics of mass spectrometry based metabolomics

F Courant, JP Antignac, G Dervilly‐Pinel… - …, 2014 - Wiley Online Library
The emerging field of metabolomics, aiming to characterize small molecule metabolites
present in biological systems, promises immense potential for different areas such as …

Synergistic action of electrolyzed water and mild heat for enhanced microbial inactivation of Escherichia coli O157: H7 revealed by metabolomics analysis

Q Liu, L Chen, AKC Laserna, Y He, X Feng, H Yang - Food Control, 2020 - Elsevier
To determine the bactericidal mechanism of electrolyzed water and mild heat against
Escherichia coli O157: H7, we performed ultra-performance liquid chromatography …