Understanding of molecular mechanisms of tumor growth has an increasing impact on the
development of diagnostics and targeted therapy of human neoplasia. In this review, we …

Background Previous studies have suggested the efficacy of HER2 antibody (trastuzumab)
in scrotal Paget's disease with HER2 amplification or overexpression. However, no report …

Background: Hemangioblastomas (HBs) typically present with benign behavior and are
most commonly found in the posterior fossa. Multiple central nervous system (CNS) HBs are …

Abstract von Hippel–Lindau (VHL) disease is characterized by neoplastic and cystic lesions,
such as central nervous system (CNS) hemangioblastoma and clear cell renal cell …

Choroidal neovascularization (CNV) is the hallmark of wet age-related macular
degeneration (AMD), a leading cause of irreversible blindness in the modern world. The …

ABSTRACT Background: Neurofibromatosis, Von Hippel Lindau disease, and tuberous
sclerosis complex are classified under the term phakomatoses. They are characterized by …

Intradural spinal tumors are rare entities in the pediatric population, which typically have
been diagnosed after many months of symptoms. Pediatric spinal tumors can be classified in …

Hemangioblastomas are WHO grade I vascularized tumors that primarily occur sporadically.
They are commonly found below the tentorium, with 5% located in the brainstem. 1 …

Introduction: Leptomeningeal dissemination of hemangioblastomas (HB) of the central
nervous system (CNS) is very rare. Few studies have reported leptomeningeal involvement …

Background. We aimed to evaluate the clinical outcomes of molecular glioblastoma (mGBM)
as compared to histological GBM (hGBM) and to determine the prognostic impact of TERT …