Cross-feeding in the gut microbiome: ecology and mechanisms
EJ Culp, AL Goodman - Cell host & microbe, 2023 - cell.com
Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
Metabolic exchanges are ubiquitous in natural microbial communities
Microbial communities drive global biogeochemical cycles and shape the health of plants
and animals—including humans. Their structure and function are determined by ecological …
and animals—including humans. Their structure and function are determined by ecological …
Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback
Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …
The mechanism of bacterial resistance and potential bacteriostatic strategies
F Zhang, W Cheng - Antibiotics, 2022 - mdpi.com
Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …
Myxobacteria restrain Phytophthora invasion by scavenging thiamine in soybean rhizosphere via outer membrane vesicle-secreted thiaminase I
C Xia, Y Zhao, L Zhang, X Li, Y Cheng, D Wang… - Nature …, 2023 - nature.com
Public metabolites such as vitamins play critical roles in maintaining the ecological functions
of microbial community. However, the biochemical and physiological bases for fine-tuning of …
of microbial community. However, the biochemical and physiological bases for fine-tuning of …
Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC
S Kamrad, C Correia-Melo, L Szyrwiel, SK Aulakh… - Nature …, 2023 - nature.com
Genetically identical cells are known to differ in many physiological parameters such as
growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such …
growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such …
Taxonomic and environmental distribution of bacterial amino acid auxotrophies
J Ramoneda, TBN Jensen, MN Price… - Nature …, 2023 - nature.com
Many microorganisms are auxotrophic—unable to synthesize the compounds they require
for growth. With this work, we quantify the prevalence of amino acid auxotrophies across a …
for growth. With this work, we quantify the prevalence of amino acid auxotrophies across a …
Joint deep autoencoder and subgraph augmentation for inferring microbial responses to drugs
Exploring microbial stress responses to drugs is crucial for the advancement of new
therapeutic methods. While current artificial intelligence methodologies have expedited our …
therapeutic methods. While current artificial intelligence methodologies have expedited our …
Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions
Background A growing body of evidence suggests that the gut microbiota is strongly linked
to general human health. Microbiome-directed interventions, such as diet and exercise, are …
to general human health. Microbiome-directed interventions, such as diet and exercise, are …
Interkingdom interactions between Pseudomonas aeruginosa and Candida albicans affect clinical outcomes and antimicrobial responses
LJ Kahl, N Stremmel, MA Esparza-Mora… - Current Opinion in …, 2023 - Elsevier
Infections that involve interkingdom microbial communities, such as those between bacteria
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …