Use of natural products in leishmaniasis chemotherapy: an overview

LFO Gervazoni, GB Barcellos, T Ferreira-Paes… - Frontiers in …, 2020 - frontiersin.org
Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus
Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the …

Recent advances in the chemical composition and biological activities of propolis

O Belmehdi, N El Menyiy, A Bouyahya… - Food Reviews …, 2023 - Taylor & Francis
Propolis is a resinous substance from beehive produced by the combination of plants and
bee secretions. For a long time, this substance has gotten high attention in traditional and …

Investigating the binding affinity, molecular dynamics, and ADMET properties of 2, 3-dihydrobenzofuran derivatives as an inhibitor of fungi, bacteria, and virus protein

A Nath, A Kumer, F Zaben, MW Khan - Beni-Suef University Journal of …, 2021 - Springer
Abstract Background 2, 3-Dihydrobenzofurans (DHB) have proposed as advantages
structures, and used as chemical entresol to design small compound libraries. The present …

Phytochemical Profiling, In Vitro Biological Activities, and In-Silico Studies of Ficus vasta Forssk.: An Unexplored Plant

HY Aati, M Anwar, J Al-Qahtani, A Al-Taweel, KR Khan… - Antibiotics, 2022 - mdpi.com
Ficus vasta Forssk.(Moraceae family) is an important medicinal plant that has not been
previously investigated for its phytochemical and biological potential. Phytochemical …

Emerging therapeutic targets for treatment of leishmaniasis

S Sundar, B Singh - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …

Antileishmanial activities of medicinal herbs and phytochemicals in vitro and in vivo: An update for the years 2015 to 2021

AA Hassan, HE Khalid, AH Abdalla, MM Mukhtar… - Molecules, 2022 - mdpi.com
Leishmaniasis is one of the most neglected tropical diseases that present areal public health
problems worldwide. Chemotherapy has several limitations such as toxic side effects, high …

Licarin A, a neolignan isolated from Nectandra oppositifolia Nees & Mart. (Lauraceae), exhibited moderate preclinical efficacy against Schistosoma mansoni …

AC Mengarda, MP Silva, ME Cirino… - Phytotherapy …, 2021 - Wiley Online Library
Schistosomiasis is a widespread human parasitic disease currently affecting over 200
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …

Evaluation of Senna tora (L.) Roxb. leaves as source of bioactive molecules with antioxidant, anti-inflammatory and antibacterial potential

MM Rahman, MA Al Noman, S Khatun, R Alam… - Heliyon, 2023 - cell.com
Abstract Senna tora (L.) Roxb. is an ethno-medicinal herb used by rural and tribal people of
the Satpura region of Madhya Pradesh in India and the Phatthalung Province of Thailand for …

Lignin from Morinda citrifolia leaves: Physical and chemical characterization, in vitro evaluation of antioxidant, cytotoxic, antiparasitic and ultrastructural activities

PR da Silva, MCA de Lima, TP Souza… - International Journal of …, 2021 - Elsevier
In this work, we investigated in vitro the antioxidant, cytotoxic and anti-leishmanial activities
of a lignin extracted from the leaves of Morinda citrifolia. Initially, an analysis of the …

Gallic and ellagic acids are promising adjuvants to conventional amphotericin B for the treatment of cutaneous leishmaniasis

MMM Alves, DDR Arcanjo, KA Figueiredo… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
In this study, we demonstrated the potential associative effect of combining conventional
amphotericin B (Amph B) with gallic acid (GA) and with ellagic acid (EA) in topical …