Uric acid is the metabolic end product of purine metabolism in humans. It has antioxidant
properties that may be protective but can also be pro-oxidant, depending on its chemical …

Rapid, accurate, portable and quantitative profiling of metabolic biomarkers is of great
importance for disease diagnosis and prognosis. The recent development in the optical and …

Recent epidemiologic studies suggest that uric acid predicts the development of new-onset
kidney disease, but it is unclear whether uric acid is an independent risk factor. In this study …

In order to make appropriate decisions about clinical management, it is important for
physicians to be able to stratify patients according to their risk for contrast-induced …

Gout is a true crystal deposition disease caused by formation of monosodium urate crystals
in joints and other tissues. It is a common inflammatory arthritis that has increased in …

BACKGROUND: Despite recent evidence, the role of uric acid as a causal factor in the
pathogenesis and progression of kidney disease remains controversial, partly because of …

Elevated plasma urate levels are associated with metabolic, cardiovascular, and renal
diseases. Urate may also form crystals, which can be deposited in joints causing gout and in …

Importance Uric acid is a waste metabolite produced from the breakdown of purines, and
elevated serum uric acid levels are associated with higher risk of hypertension …

Objective Renal impairment is a risk factor for gout and a barrier to optimal gout
management. We undertook this exploratory study to obtain data that have been heretofore …

In the years after introduction of effective urate-lowering therapy, many persons who had
hyperuricemia but no symptoms of gout were treated with allopurinol or uricosuric agents in …