Recent advances in biotechnological applications of alcohol dehydrogenases

YG Zheng, HH Yin, DF Yu, X Chen, XL Tang… - Applied microbiology …, 2017 - Springer
Alcohol dehydrogenases (ADHs), which belong to the oxidoreductase superfamily, catalyze
the interconversion between alcohols and aldehydes or ketones with high stereoselectivity …

Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions

A Chadha, S Venkataraman, R Preetha, SK Padhi - Bioorganic chemistry, 2016 - Elsevier
This review highlights the importance of the biocatalyst, Candida parapsilosis for oxidation
and reduction reactions of organic compounds and establishes its versatility to generate a …

Classification and functional origins of stereocomplementary alcohol dehydrogenases for asymmetric synthesis of chiral secondary alcohols: A review

L Zhang, Z Sun, G Xu, Y Ni - International Journal of Biological …, 2024 - Elsevier
Alcohol dehydrogenases (ADHs) mediated biocatalytic asymmetric reduction of ketones
have been widely applied in the synthesis of optically active secondary alcohols with highly …

A carbonyl reductase from Candida parapsilosis ATCC 7330: substrate selectivity and enantiospecificity

S Sudhakara, A Chadha - Organic & Biomolecular Chemistry, 2017 - pubs.rsc.org
Candida parapsilosis ATCC 7330, a rich source of highly stereospecific oxidoreductases,
catalyzes oxidation–reduction of a plethora of compounds yielding industrially important …

Stereochemical preference of Candida parapsilosis ATCC 7330 mediated deracemization: E-versus Z-aryl secondary alcohols

T Saravanan, R Selvakumar, M Doble… - Tetrahedron: Asymmetry, 2012 - Elsevier
The stereochemical preference of the biocatalyst, Candida parapsilosis ATCC 7330, was
investigated with respect to the E/Z configuration in the deracemization and the asymmetric …

Biocatalytic deracemisation of aliphatic β-hydroxy esters: Improving the enantioselectivity by optimisation of reaction parameters

S Venkataraman, A Chadha - Journal of Industrial Microbiology …, 2015 - academic.oup.com
Optically pure aliphatic β-hydroxy esters were prepared from their racemates by
deracemisation using the biocatalyst Candida parapsilosis ATCC 7330. High optical purity …

Asymmetric Reduction of Alkyl-3-oxobutanoates by Candida parapsilosis ATCC 7330: Insights into Solvent and Substrate Optimisation of the Biocatalytic Reaction

S Venkataraman, RK Roy, A Chadha - Applied biochemistry and …, 2013 - Springer
Asymmetric reduction of alkyl-3-oxobutanoates mediated by Candida parapsilosis ATCC
7330 resulted in optically pure alkyl-3-hydroxybutanoates in good yields (up to 72%) and …

Expression, purification, crystallization and preliminary X-ray diffraction analysis of carbonyl reductase from Candida parapsilosis ATCC 7330

N Aggarwal, PK Mandal, N Gautham… - … Section F: Structural …, 2013 - journals.iucr.org
The NAD (P) H-dependent carbonyl reductase from Candida parapsilosis ATCC 7330
catalyses the asymmetric reduction of ethyl 4-phenyl-2-oxobutanoate to ethyl (R)-4-phenyl-2 …

Enantio-& chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330

S Venkataraman, A Chadha - RSC advances, 2015 - pubs.rsc.org
Enantiomerically pure β-and γ-nitro alcohols were prepared from their respective nitro
ketones by asymmetric reduction mediated by the biocatalyst, Candida parapsilosis ATCC …

A study on increasing enzymatic stability and activity of Baliospermum montanum hydroxynitrile lyase in biocatalysis

N Jangir, SK Padhi - Process Biochemistry, 2020 - Elsevier
HNL catalysis is usually carried out in a biphasic solvent and at low pH to suppress the non-
enzymatic synthesis of racemic cyanohydrins. However, enzyme stability under these …