ACE inhibitors effectively reduce systemic vascular resistance in patients with hypertension,
heart failure or chronic renal disease. This antihypertensive efficacy probably accounts for …

Captopril is an orally active inhibitor of angiotensin-converting enzyme (ACE) and has been
widely studied in the treatment of patients with mild to moderate essential hypertension …

Angiotensin converting enzyme (ACE) inhibitors are now one of the most frequently used
classes of antihypertensive drugs. Beyond their utility in the management of hypertension …

The effect on renal function of long-term treatment with either enalapril (n= 123) or placebo
(n= 120) in addition to conventional therapy was studied in a randomized trial in patients …

Renal function was evaluated in 104 patients with severe chronic heart failure whom we
treated with Captopril or enalapril. Seventy patients showed no change or an improvement …

When renal perfusion pressure is reduced in experimentally induced low-output states,
glomerular filtration rate is preserved by angiotensin II-mediated efferent arteriolar …

In congestive heart failure (CHF), hemofiltration is associated with an obvious decrease in
circulating norepinephrine. This method was used for investigating the mechanisms …

Blood pressure declines in virtually all patients with severe congestive heart failure given an
angiotensin-converting enzyme (ACE) inhibitor, but hypotension is of concern only if …

The inter-relationship between the pharmacokinetic and pharmacodynamic behaviour of
ACE inhibitors is reviewed. First, some of the methods which have been used to assess the …

In 14 patients with severe congestive heart failure, the effects of captopril on the forearm
circulation were evaluated with strain gauge plethysmography. Changes in plasma renin …