[PDF][PDF] The vascular perspective on acute and chronic lung disease

I Borek, A Birnhuber, NF Voelkel… - Journal of Clinical …, 2023 - Am Soc Clin Investig
The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …

Animal models of pulmonary hypertension: Getting to the heart of the problem

JP Dignam, TE Scott, BK Kemp‐Harper… - British Journal of …, 2022 - Wiley Online Library
Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …

Effect of pulmonary hypertension on exercise tolerance in patients with COPD: a prognostic systematic review and meta-analysis

R Torres-Castro, E Gimeno-Santos… - European …, 2021 - Eur Respiratory Soc
Background Pulmonary hypertension (PH) is a frequent complication in patients with COPD.
Objective To determine if, in patients with COPD, the presence of PH decreases exercise …

Updated perspectives on pulmonary hypertension in COPD

I Blanco, O Tura-Ceide, VI Peinado… - International Journal of …, 2020 - Taylor & Francis
Pulmonary hypertension (PH) is a frequent and important complication of chronic obstructive
pulmonary disease (COPD). It is associated with worse clinical courses with more frequent …

Insights into chronic obstructive pulmonary disease as critical risk factor for cardiovascular disease

P Almagro, R Boixeda, J Diez-Manglano… - … journal of chronic …, 2020 - Taylor & Francis
In patients with chronic obstructive pulmonary disease (COPD), cardiovascular
comorbidities are highly prevalent and associated with considerable morbidity and mortality …

[HTML][HTML] Role of prostanoids, nitric oxide and endothelin pathways in pulmonary hypertension due to COPD

AA Alqarni, AM Aldhahir, SA Alghamdi… - Frontiers in …, 2023 - frontiersin.org
Pulmonary hypertension (PH) due to chronic obstructive pulmonary disease (COPD) is
classified as Group 3 PH, with no current proven targeted therapies. Studies suggest that …

Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations

ET Roxlau, O Pak, S Hadzic… - European …, 2023 - Eur Respiratory Soc
Background Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …

[HTML][HTML] FVC/DLCO identifies pulmonary hypertension and predicts 5-year all-cause mortality in patients with COPD

Y Li, R Zhang, H Shan, W Shi, X Feng, H Chen… - European Journal of …, 2023 - Springer
Background Pulmonary hypertension (PH) is a common complication of chronic obstructive
pulmonary disease (COPD). However, it is unknown whether the ratio of forced vital capacity …

Heightened long-term cardiovascular risks after exacerbation of chronic obstructive pulmonary disease

NM Hawkins, C Nordon, K Rhodes, M Talukdar… - Heart, 2024 - heart.bmj.com
Objective To examine the risk of adverse cardiovascular (CV) events following an
exacerbation of chronic obstructive pulmonary disease (COPD). Methods This retrospective …

Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice

M Gredic, CY Wu, S Hadzic, O Pak… - European …, 2022 - Eur Respiratory Soc
Background Pulmonary hypertension (PH) is a common complication of COPD, associated
with increased mortality and morbidity. Intriguingly, pulmonary vascular alterations have …