[PDF][PDF] Arrhythmia risk and obesity

I Mozos - Journal of Molecular and Genetic Medicine, 2014 - researchgate.net
Arrhythmia Risk and Obesity Page 1 ISSN: 1747-0862 Journal of Molecular and Genetic Medicine
The International Open Access Journal of Molecular and Genetic Medicine Special Issue Title …

Myocardial susceptibility to ischaemia/reperfusion in obesity: a re-evaluation of the effects of age

I Webster, R Salie, E Marais, WJ Fan, G Maarman… - BMC physiology, 2017 - Springer
Background Reports on the effect of age and obesity on myocardial ischaemia/reperfusion
(I/R) injury and ischaemic preconditioning are contradictory. The aim of this study was to re …

Impact of diet-induced obesity and testosterone deficiency on the cardiovascular system: a novel rodent model representative of males with Testosterone-Deficient …

DG Donner, GE Elliott, BR Beck, AC Bulmer… - PLoS …, 2015 - journals.plos.org
Introduction Current models of obesity utilise normogonadic animals and neglect the strong
relationships between obesity-associated metabolic syndrome (MetS) and male …

[PDF][PDF] The effects of gender and obesity on myocardial tolerance to ischemia

C Clark, W Smith, A Lochner, EF Du Toit - Physiological Research, 2011 - researchgate.net
Obesity is increasing at an alarming rate globally. Several studies have shown that
premenopausal women have a reduced risk of CV disease and a reduced myocardial …

Roles of p38-MAPK in insulin resistant heart: evidence from bench to future bedside application

S Kumphune, S Chattipakorn… - Current pharmaceutical …, 2013 - ingentaconnect.com
Insulin resistance is associated with the impairment of the response of insulin receptor to
insulin, resulting in the reduction of glucose uptake, leading to the alteration of myocardial …

Relationship of cardiac remodeling and perfusion alteration with hepatic lipid metabolism in a prediabetic high fat high sucrose diet female rat model

A Jouenne, K Hamici, I Varlet, J Sourdon… - Biochemical and …, 2023 - Elsevier
Background and aims Cardiovascular disease (CVD) is known to be linked with metabolic
associated fatty liver disease and type 2 diabetes, but few studies assessed this relationship …

Impaired contractile function and mitochondrial respiratory capacity in response to oxygen deprivation in a rat model of pre‐diabetes

MF Essop, WY Anna Chan, A Valle… - Acta …, 2009 - Wiley Online Library
Aim: Obesity is a major contributor to the global burden of disease and is closely associated
with the development of type 2 diabetes and cardiovascular diseases. This study tested the …

Stress‐induced body weight loss and improvements in cardiometabolic risk factors do not translate to improved myocardial ischemic tolerance in western diet‐fed …

K Hatton‐Jones, AJ Cox, JN Peart… - Physiological …, 2022 - Wiley Online Library
Although both diet‐induced obesity and psychological stress are recognized as significant
independent contributors to cardiometabolic and behavioral disorders, our understanding of …

Developmental programming resulting from maternal obesity in mice: effects on myocardial ischaemia–reperfusion injury

JW Calvert, DJ Lefer, S Gundewar… - Experimental …, 2009 - Wiley Online Library
A comprehensive number of epidemiological and animal studies suggest that prenatal and
early life events are important determinants for disorders later in life. Among them, prenatal …

TAT delivery of a PTEN peptide inhibitor has direct cardioprotective effects and improves outcomes in rodent models of cardiac arrest

X Zhu, J Li, H Wang, FM Gasior, C Lee… - American Journal …, 2021 - journals.physiology.org
We have recently shown that pharmacologic inhibition of PTEN significantly increases
cardiac arrest survival in a mouse model, however, this protection required pretreatment 30 …