[HTML][HTML] Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies

S Pokhrel, BR Kraemer, S Burkholz… - Scientific reports, 2021 - nature.com
In December 2019, a novel coronavirus, termed severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), was identified as the cause of pneumonia with severe …

Could pyrimidine derivative be effective against Omicron of SARS-CoV-2?

H KARATAŞ, T Burak, K Zulbiye - Bratislava Medical Journal, 2022 - avesis.kayseri.edu.tr
© 2022. Bratislava Medical Journal. All Rights Reserved. BACKGROUND: A pyrimidine
based Schiff base was examined in this report. Structural and spectral characterizations …

[HTML][HTML] Does COVID-19 Vaccination Warrant the Classical Principle “ofelein i mi vlaptin”?

M Doulberis, A Papaefthymiou, G Kotronis… - Medicina, 2021 - mdpi.com
The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
warrants an imperative necessity for effective and safe vaccination, to restrain Coronavirus …

[HTML][HTML] Therapeutic antibodies and alternative formats against SARS-CoV-2

RR Winiger, L Perez - Antiviral Research, 2024 - Elsevier
The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) heavily burdened the entire world. Despite a prompt generation of vaccines …

[HTML][HTML] Early-stage spatial disease surveillance of novel SARS-CoV-2 variants of concern in Germany with crowdsourced data

T Mitze, J Rode - Scientific Reports, 2022 - nature.com
The emergence and rapid spread of novel variants of concern (VOC) of the coronavirus 2
constitute a major challenge for spatial disease surveillance. We explore the possibility to …

[HTML][HTML] VirusLab: a tool for customized SARS-CoV-2 data analysis

P Pinoli, A Bernasconi, A Sandionigi, S Ceri - BioTech, 2021 - mdpi.com
Since the beginning of 2020, the COVID-19 pandemic has posed unprecedented
challenges to viral data analysis and connected host disease diagnostic methods. We …

The value of medical registries and observational studies early in pandemics: the coronavirus disease 2019 (COVID-19) experience

S Albhaisi, RP Wenzel - Clinical Infectious Diseases, 2022 - academic.oup.com
Whereas randomized clinical trials remain the gold standard for evaluating new therapies for
infections, we argue that registries and observational studies early in the coronavirus …

[HTML][HTML] IDbSV: an open-access repository for monitoring sars-cov-2 variations and evolution

A Essabbar, S Kartti, T Alouane, M Hakmi… - Frontiers in …, 2021 - frontiersin.org
Ending COVID-19 pandemic requires a collaborative understanding of SARS-CoV-2 and
COVID-19 mechanisms. Yet, the evolving nature of coronaviruses results in a continuous …

CoVe-tracker: an interactive SARS-CoV-2 Pan proteome evolution tracker

C Sathyaseelan… - Journal of Proteome …, 2023 - ACS Publications
SARS-CoV-2 has significantly mutated its genome during the past 3 years, leading to the
periodic emergence of several variants. Some of the variants possess enhanced fitness …

[HTML][HTML] AutoVEM: An automated tool to real-time monitor epidemic trends and key mutations in SARS-CoV-2 evolution

B Xi, D Jiang, S Li, JR Lon, Y Bai, S Lin, M Hu… - Computational and …, 2021 - Elsevier
With the global epidemic of SARS-CoV-2, it is important to effectively monitor the variation,
haplotype subgroup epidemic trends and key mutations of SARS-CoV-2 over time. This is of …