Neuroinflammation following traumatic brain injury: take it seriously or not

R Zheng, K Lee, Z Qi, Z Wang, Z Xu, X Wu… - Frontiers in …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …

COVID-19 and Long COVID: disruption of the neurovascular unit, blood-brain barrier, and tight junctions

D Kempuraj, KK Aenlle, J Cohen… - The …, 2023 - journals.sagepub.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …

The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury

ME Huibregtse, JJ Bazarian, SR Shultz… - … & Biobehavioral Reviews, 2021 - Elsevier
Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Opportunities and challenges for microRNA-targeting therapeutics for epilepsy

G Morris, D O'Brien, DC Henshall - Trends in Pharmacological Sciences, 2021 - cell.com
Epilepsy is a common and serious neurological disorder characterised by recurrent
spontaneous seizures. Frontline pharmacotherapy includes small-molecule antiseizure …

Extracellular vesicles in neurodegenerative diseases: A systematic review

A Raghav, M Singh, GB Jeong, R Giri… - Frontiers in molecular …, 2022 - frontiersin.org
Introduction Extracellular vesicles (EVs) are known to have a significant role in the central
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …

The exosome-mediated PI3K/Akt/mTOR signaling pathway in neurological diseases

A Iranpanah, L Kooshki, SZ Moradi, L Saso, S Fakhri… - Pharmaceutics, 2023 - mdpi.com
As major public health concerns associated with a rapidly growing aging population,
neurodegenerative diseases (NDDs) and neurological diseases are important causes of …

[HTML][HTML] Extracellular vesicles in mental disorders: a state-of-art review

L Kong, D Zhang, S Huang, J Lai, L Lu… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are nanoscale particles with various physiological functions
including mediating cellular communication in the central nervous system (CNS), which …

Extracellular microvesicles promote microgliamediated proinflammatory responses to ethanol

FT Crews, J Zou, LG Coleman Jr - Journal of neuroscience …, 2021 - Wiley Online Library
Alcohol use disorder (AUD) pathology features proinflammatory gene induction and
microglial activation. The underlying cellular processes that promote this activation remain …

Mesenchymal stem cell-derived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration

Y Xiong, A Mahmood, M Chopp - Neural Regeneration Research, 2024 - journals.lww.com
Traumatic brain injury is a serious and complex neurological condition that affects millions of
people worldwide. Despite significant advancements in the field of medicine, effective …

Challenges in biomaterial-based drug delivery approach for the treatment of neurodegenerative diseases: Opportunities for extracellular vesicles

A Kumar, L Zhou, K Zhi, B Raji, S Pernell… - International Journal of …, 2020 - mdpi.com
Biomaterials have been the subject of numerous studies to pursue potential therapeutic
interventions for a wide variety of disorders and diseases. The physical and chemical …