Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Retinal biomarkers in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis

YJ Ge, W Xu, YN Ou, Y Qu, YH Ma, YY Huang… - Ageing Research …, 2021 - Elsevier
Background Retinal changes may reflect the pathophysiological processes in the central
nervous system and can be assessed by imaging modalities non-invasively. We aim to …

[HTML][HTML] Alzheimer's disease pathophysiology in the retina

BP Gaire, Y Koronyo, DT Fuchs, H Shi… - Progress in Retinal and …, 2024 - Elsevier
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

[HTML][HTML] Retinal neurodegeneration in diabetes: an emerging concept in diabetic retinopathy

MM Sachdeva - Current diabetes reports, 2021 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR), the leading cause of blindness in
working-aged adults, remains clinically defined and staged by its vascular manifestations …

[HTML][HTML] Retinal microvasculature dysfunction is associated with Alzheimer's disease and mild cognitive impairment

J Chua, Q Hu, M Ke, B Tan, J Hong, X Yao… - Alzheimer's Research & …, 2020 - Springer
Abstracts Background The retina and brain share many neuronal and vasculature
characteristics. We investigated the retinal microvasculature in Alzheimer's disease (AD) …

[HTML][HTML] Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer's disease patients

S Lemmens, T Van Craenendonck… - Alzheimer's research & …, 2020 - Springer
Introduction The eye offers potential for the diagnosis of Alzheimer's disease (AD) with
retinal imaging techniques being explored to quantify amyloid accumulation and aspects of …

Width attention based convolutional neural network for retinal vessel segmentation

DE Alvarado-Carrillo, OS Dalmau-Cedeño - Expert Systems with …, 2022 - Elsevier
The analysis of the vascular tree is a fundamental part of the clinical assessment of retinal
images. The diversity of blood vessel calibers and curvatures, as well as the ocular vascular …

Optical coherence tomography in patients with Alzheimer's disease: what can it tell us?

A Song, N Johnson, A Ayala, AC Thompson - Eye and brain, 2021 - Taylor & Francis
Purpose Although Alzheimer's disease (AD) is a leading cause of dementia worldwide, its
clinical diagnosis remains a challenge. Optical coherence tomography (OCT) and OCT with …

[HTML][HTML] Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders

E Boudriot, B Schworm, L Slapakova, K Hanken… - European Archives of …, 2023 - Springer
Abstract Background Schizophrenia spectrum disorders (SSDs) are presumed to be
associated with retinal thinning. However, evidence is lacking as to whether these retinal …

[HTML][HTML] The retina: A window in which to view the pathogenesis of Alzheimer's disease

J Zhang, L Shi, Y Shen - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …