Patient-relevant outcomes: what are we talking about? A scoping review to improve conceptual clarity

C Kersting, M Kneer, A Barzel - BMC health services research, 2020 - Springer
Background With respect to patient-centered care, measuring care effects based on patient-
relevant outcomes is becoming increasingly important. There is some uncertainty about …

Traditional Chinese medicine for coronary artery disease treatment: clinical evidence from randomized controlled trials

B Liang, N Gu - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Traditional Chinese medicine has a history of more than 2,000 years and has been widely
used in clinical practice. However, due to the lack of a reliable scientific basis, the role of …

Enhancement of oral bioavailability of curcumin by a novel solid dispersion system

L Hu, Y Shi, JH Li, N Gao, J Ji, F Niu, Q Chen, X Yang… - Aaps Pharmscitech, 2015 - Springer
The objective of this study was to improve the solubility and bioavailability of curcumin by a
new curcumin dripping pills (Cur-DPs) formulation using melt mixing methods. The optimal …

Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease

B Liu, Y Du, L Cong, X Jia… - … Based Complementary and …, 2016 - Wiley Online Library
Danshen was able to reduce the risk of the patients with coronary heart disease (CHD), but
the mechanism is still widely unknown. Biochemical indices (lipid profile, markers of renal …

Tongxinluo protects against hypertensive kidney injury in spontaneously-hypertensive rats by inhibiting oxidative stress and activating forkhead box O1 signaling

W Luo, J Kong, Y Gong, X Liu, R Yang, Y Zhao - PloS one, 2015 - journals.plos.org
Hypertension is an independent risk factor for the progression of chronic renal failure, and
oxidative stress plays a critical role in hypertensive renal damage. Forkbox O1 (FoxO1) …

Identification of more objective biomarkers for Blood-Stasis syndrome diagnosis

J Liao, Y Liu, J Wang - BMC Complementary and Alternative Medicine, 2016 - Springer
Background Blood-stasis syndrome (BSS) is one of the Traditional Chinese medicine (TCM)
syndrome differentiations that are commonly seen in stroke and ischemic heart diseases; …

An integrated evidence-based targeting strategy for determining combinatorial bioactive ingredients of a compound herbal medicine Qishen Yiqi dripping pills

Y Zhang, J Yu, W Zhang, Y Wang, Y He, S Zhou… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Qishen Yiqi is a widely used Chinese herbal
medicine formula with “qi invigorating and blood activating” property. Its dripping pill …

Simultaneous determination of eight bioactive components of Qishen Yiqi Dripping Pills in rat plasma using UFLC–MS/MS and its application to a pharmacokinetic …

Y Shao, W Zhang, L Tong, J Huang, D Li… - Biomedical …, 2017 - Wiley Online Library
In this study, a rapid and reliable ultra‐fast liquid chromatography–tandem mass
spectrometry method was developed and validated for the simultaneous determination of …

Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta‐Analysis of 85 Studies

H Wang, L Li, X Qing, S Zhang… - Cardiovascular …, 2020 - Wiley Online Library
Background. Despite evidence for beneficial effects of Qishen Yiqi Drop Pill (QSYQ) on
congestive heart failure, the majority of studies are based on insufficient sample sizes. The …

Network Pharmacology and In Vivo Analysis of Dahuang‐Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis

Y Luo, C Xuan, J Cheng, Y Xiong… - … and Alternative Medicine, 2022 - Wiley Online Library
Dahuang and Huangqi are the most frequently prescribed treatment methods for chronic
kidney disease in China. Our study aimed to clarify the pharmacological mechanism of …