The study of angiogenesis has grown exponentially over the past 40 years with the
recognition that angiogenesis is essential for numerous pathologies and, more recently, with …

An integrative approach for managing a patient with cancer should target the multiple
biochemical and physiologic pathways that support tumour development and minimize …

The number of anticancer agents that fail in the clinic far outweighs those considered
effective, suggesting that the selection procedure for progression of molecules into the clinic …

An integrative approach for managing a patient with cancer should target the multiple
biochemical and physiological pathways that support tumor development while minimizing …

All living beings continue their life by receiving energy and by excreting waste products. In
animals, the arteries are the pathways of these transfers to the cells. Angiogenesis, the …

Chemokines, a large family of inflammatory cytokines, have been shown to play a critical
role in the regulation of angiogenesis during several pathophysiologic processes, such as …

Between 2000 and 2050, the number of new cancer patients diagnosed annually is
expected to double, with an accompanying increase in treatment costs of more than $80 …

Abstract Kisspeptin-10 (Kp-10), a decapeptide derived from the primary translation product
of KISS1 gene, has been reported previously to be a key hormone for puberty and an …

Our previous studies have shown that benzyl isothiocyanate (BITC) suppresses pancreatic
tumor growth by inhibiting STAT-3; however, the exact mechanism of tumor growth …

The intrinsic complexity of the process of vessel formation limits the efficacy of cellular
assays for elucidation of its molecular and pharmacologic mechanisms. We developed an …