Chondrosarcomas are a diverse group of malignant cartilaginous matrix-producing
neoplasms. Conventional chondrosarcomas are a continuum of disease based on the …

Introduction: Human chondrosarcomas (CS; a malignant cartilage-forming bone tumor)
respond poorly to chemotherapy and radiation treatment, resulting in high morbidity and …

PURPOSE Surgery is the primary therapy for localized chondrosarcoma; for locally
advanced and/or metastatic disease, no known effective systemic therapy exists. Mutations …

Chondrosarcomas are rare tumors and, historically, investigation of these tumors has been
limited to small series and single‐institution studies. There have been no studies that …

Background Several studies have identified prognostic factors for patients with
chondrosarcoma, but there are few studies investigating the accuracy of computationally …

Bone sarcomas are devastating primary bone cancers that mostly affect children, young
adults, and the elderly. These aggressive tumors are associated with poor survival, and …

Introduction The role of chemotherapy for patients with dedifferentiated chondrosarcoma
(DDCS) is still under discussion. Here, we present the outcome in patients with DDCS …

Background. Dedifferentiated chondrosarcomas (DDCSs) are highly malignant tumors with
a dismal prognosis and present a significant challenge in clinical management. Methods. In …

Abstract Purpose of Review The pathogenesis of dedifferentiated chondrosarcoma is
controversial, and no genetic abnormality has consistently been identified in the disease …

Objectives Cartilaginous bone tumors represent a wide variety of neoplasms ranging from
benign to extremely aggressive malignant lesions. Unlike other tumors, the biopsy cannot …