The intraocular pressure rise that can complicate the use of topical or systemic corticosteroid
has been recognised for 50 years. More recently, following isolation of the myocilin gene …

Based on clinical experiments with fluorophotometry, several observations can be made
about aqueous flow through the chambers of the human eye. 1. The rate of flow is 2.75+ …

• The prognosis for vision in most patients with pseudotumor cerebri is excellent; however,
visual loss, which is the only serious complication, may occur either early or late in the …

In a preceding publication, 1 the topical application of dexamethasone* in the normal eye
was shown to produce a significant increase in intraocular pressure and a reduction in …

Steroids in susceptible individuals can cause a clinical condition similar to primary open-
angle glaucoma. Five percent of the population are high steroid responders and develop an …

PURPOSE: To determine the effects of glucocorticoid treatment on the microfilament
structure of cultured human trabecular meshwork cells. Topical or systemic administration of …

Steroids are invaluable agents in the treatment of a diverse spectrum of disorders; however,
their use is not without risks. Topical, periocular, and systemic steroids may cause ocular …

Introduction The finding of γ-globulin and plasma cells in the trabecular meshwork of
glaucomatous eyes suggested an immunogenic component. 1, 2 The present study was …

Glucocorticoid effects on the human trabecular meshwork can be used as a model system in
which to study glaucomatous damage to the trabecular meshwork. One of the most important …

Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called
steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma …