Glucocorticoid-Induced Ocular Hypertension and Glaucoma

DH Harvey, CK Sugali, W Mao - Clinical Ophthalmology, 2024 - Taylor & Francis
Glucocorticoid (GC) therapy is indicated in many diseases, including ocular diseases. An
important side-effect of GC therapy is GC-induced ocular hypertension (GIOHT), which may …

Visual loss caused by corticosteroid-induced glaucoma: how to avoid it

GL Spaeth, DSM de Barros, SJ Fudemberg - Retina, 2009 - journals.lww.com
The initial report of elevation of intraocular pres-sure (IOP) in response to corticosteroids
was that by McLean, 1 who, in 1950, noted that adrenocorticotropic hormone (ACTH) could …

Early and frequent development of ocular hypertension in children with nephrotic syndrome

E Kawaguchi, K Ishikura, R Hamada, Y Nagaoka… - Pediatric …, 2014 - Springer
Background Prednisolone, the first-line treatment for children with nephrotic syndrome,
causes severe side effects. One of these side effects is ocular hypertension, which can result …

[PDF][PDF] Toxic reactions and side effects of glucocorticoids in man

WS Bond - American Journal of Health-System Pharmacy, 1977 - oxfordjournals.org
The toxic reactions and side effects of glucocorticoids in humans are discussed. The effects
reviewed include metabolic (muscle and skin, carbohydrates and lipids), cardioн vascular …

Effects of dexamethasone on sodium-potassium-chloride cotransport in trabecular meshwork cells.

LK Putney, JD Brandt… - … ophthalmology & visual …, 1997 - iovs.arvojournals.org
PURPOSE: Previous studies in the authors' laboratory have shown that bovine and human
trabecular meshwork (TM) cells possess a robust sodium-potassium-chloride (Na-K-Cl) …

[HTML][HTML] Unique response profile of trabecular meshwork cells to the novel selective glucocorticoid receptor agonist, GW870086X

WD Stamer, EA Hoffman, E Kurali… - … ophthalmology & visual …, 2013 - tvst.arvojournals.org
Purpose.: Glucocorticoid (GC)-induced glaucoma is an undesirable side effect of traditional
GCs. Ocular hypertension responsible for GC-induced glaucoma is due to alterations in …

[HTML][HTML] Changes in Intraocular Pressure with Use of Periocular Triamcinolone Cream

DH Kim, SA Bautista, E Meer, B McGeehan… - Journal of Ophthalmic …, 2022 - ncbi.nlm.nih.gov
Methods A retrospective chart review identified 57 patients, 114 eyes using triamcinolone
cream (0.1%, 0.025%) with subsequent intraocular pressure (IOP) checks at three follow-up …

[HTML][HTML] Incidence and Outcomes of Hypertensive Phase After Glaucoma Drainage Device Surgery

M Tang, N Gill, AP Tanna - Ophthalmology Glaucoma, 2024 - Elsevier
Purpose To describe the incidence, risk factors, clinical characteristics, and long-term
outcomes of a hypertensive phase (HP) after glaucoma drainage device (GDD) implantation …

Reduced plasma cortisol binding to albumin in ocular hypertension and primary open-angle glaucoma

GR McCarty, B Schwartz - Current eye research, 1999 - Taylor & Francis
Purpose. To compare plasma cortisol binding as well as total plasma cortisol, free cortisol
and percent free cortisol in normals, ocular hypertensives and primary high pressure open …

Topical corticosteroids and aqueous humor dynamics

JP NICHOLAS - Archives of Ophthalmology, 1964 - jamanetwork.com
Locally and systemically administered corticosteroids have been implicated as a causative
factor in the elevation of intraocular pressure. 1-7 Recently, the extensive studies of Armaly …