The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
[HTML][HTML] Bacterial genome sequencing in clinical microbiology: a pathogen-oriented review
In recent years, whole-genome sequencing (WGS) has been perceived as a technology with
the potential to revolutionise clinical microbiology. Herein, we reviewed the literature on the …
the potential to revolutionise clinical microbiology. Herein, we reviewed the literature on the …
Same-day diagnostic and surveillance data for tuberculosis via whole-genome sequencing of direct respiratory samples
AA Votintseva, P Bradley, L Pankhurst… - Journal of clinical …, 2017 - Am Soc Microbiol
Routine full characterization of Mycobacterium tuberculosis is culture based, taking many
weeks. Whole-genome sequencing (WGS) can generate antibiotic susceptibility profiles to …
weeks. Whole-genome sequencing (WGS) can generate antibiotic susceptibility profiles to …
[HTML][HTML] Genomic characterization of nontuberculous mycobacteria
T Fedrizzi, CJ Meehan, A Grottola, E Giacobazzi… - Scientific reports, 2017 - nature.com
Mycobacterium tuberculosis and Mycobacterium leprae have remained, for many years, the
primary species of the genus Mycobacterium of clinical and microbiological interest. The …
primary species of the genus Mycobacterium of clinical and microbiological interest. The …
[HTML][HTML] High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain
Y Xu, I Cancino-Muñoz, M Torres-Puente… - PLoS …, 2019 - journals.plos.org
Background Whole genome sequencing provides better delineation of transmission clusters
in Mycobacterium tuberculosis than traditional methods. However, its ability to reveal …
in Mycobacterium tuberculosis than traditional methods. However, its ability to reveal …
[HTML][HTML] Interpreting whole genome sequencing for investigating tuberculosis transmission: a systematic review
Background Whole genome sequencing (WGS) is becoming an important part of
epidemiological investigations of infectious diseases due to greater resolution and cost …
epidemiological investigations of infectious diseases due to greater resolution and cost …
[HTML][HTML] Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential?
Background Nearly two decades after completion of the genome sequence of
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …
Comprehensive whole-genome sequencing and reporting of drug resistance profiles on clinical cases of Mycobacterium tuberculosis in New York State
J Shea, TA Halse, P Lapierre, M Shudt… - Journal of clinical …, 2017 - Am Soc Microbiol
Whole-genome sequencing (WGS) is a newer alternative for tuberculosis (TB) diagnostics
and is capable of providing rapid drug resistance profiles while performing species …
and is capable of providing rapid drug resistance profiles while performing species …
Standard genotyping overestimates transmission of Mycobacterium tuberculosis among immigrants in a low-incidence country
Immigrants from regions with a high incidence of tuberculosis (TB) are a risk group for TB in
low-incidence countries such as Switzerland. In a previous analysis of a nationwide …
low-incidence countries such as Switzerland. In a previous analysis of a nationwide …
[HTML][HTML] A quantitative evaluation of MIRU-VNTR typing against whole-genome sequencing for identifying Mycobacterium tuberculosis transmission: a prospective …
DH Wyllie, JA Davidson, EG Smith, P Rathod… - …, 2018 - thelancet.com
Abstract Background Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem
Repeat (MIRU-VNTR) typing is widely used in high-income countries to determine …
Repeat (MIRU-VNTR) typing is widely used in high-income countries to determine …