Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

It has been well established that the etiopathogenesis of diverse autoimmune diseases is
rooted in the autoreactive immune cells' excessively proliferative state and impaired …

The observed incidence of psoriasis has been gradually increasing over time (J Am Acad
Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear …

Aims: In this study, we aimed to decipher the impact of enhancer of zeste homolog 2 (EZH2)
in psoriasis as well as the underlying mechanism. Methods: A mouse model of psoriasis was …

MicroRNAs (miRNAs), which mostly cause target gene silencing via transcriptional
repression and degradation of target mRNAs, regulate a plethora of cellular activities, such …

Psoriasis is a chronic inflammatory skin disorder that impairs the quality of life of affected
patients. Emerging studies indicate that certain long non‑coding RNAs (lncRNAs) have …

High plasma lactate is emerging as a critical regulator in development and progression of
many human malignancies. Small RNAs derived from cleavage of mature tRNAs have been …

Anlotinib is a novel molecular targeted agent targeting the vascular endothelial growth factor
receptor, which differs from the other currently available non-small cell lung cancer (NSCLC) …

Background Scatophagus argus is a popular farmed fish in several countries of Southeast
Asia, including China. Although S. argus has a highly promising economic value, a …

Background The pregnane X receptor (PXR) not only plays an important role in cellular
metabolism processes but also induces the resistance of hepatocellular carcinoma (HCC) …