[HTML][HTML] Control of myeloid cell functions by nociceptors

P Hanč, MA Messou, Y Wang… - Frontiers in …, 2023 - frontiersin.org
The immune system has evolved to protect the host from infectious agents, parasites, and
tumor growth, and to ensure the maintenance of homeostasis. Similarly, the primary function …

[HTML][HTML] Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegans

F Marques, L Falquet, E Vandewyer, I Beets… - PLoS …, 2021 - journals.plos.org
In order to thrive in constantly changing environments, animals must adaptively respond to
threatening events. Noxious stimuli are not only processed according to their absolute …

[HTML][HTML] CKR-1 orchestrates two motor states from a single motoneuron in C. elegans

L Chen, P Su, Y Wang, Y Liu, LM Chen, S Gao - Iscience, 2024 - cell.com
Neuromodulation is pivotal in modifying neuronal properties and motor states. CKR-1, a
homolog of the cholecystokinin receptor, modulates robust escape steering and undulation …

Diverse identities and sites of action of cochlear neurotransmitters

SR Kitcher, AM Pederson, CJC Weisz - Hearing research, 2022 - Elsevier
Accurate encoding of acoustic stimuli requires temporally precise responses to sound
integrated with cellular mechanisms that encode the complexity of stimuli over varying …

CGRP, amylin, immunology, and headache medicine

FR Taylor - Headache: The Journal of Head and Face Pain, 2019 - Wiley Online Library
Background Calcitonin gene‐related peptide (CGRP) therapeutics introduce new
excitement and possibly yet to be determined distressing discords in the field of Headache …

CGRP-based migraine therapeutics: how might they work, why so safe, and what next?

AF Russo - ACS pharmacology & translational science, 2018 - ACS Publications
Migraine is a debilitating neurological condition that involves the neuropeptide calcitonin
gene-related peptide (CGRP). An exciting development is the recent FDA approval of the …

HyPep: An open-source software for identification and discovery of neuropeptides using sequence homology search

NQ Vu, HC Yen, L Fields, W Cao… - Journal of proteome …, 2023 - ACS Publications
Neuropeptides are a class of endogenous peptides that have key regulatory roles in
biochemical, physiological, and behavioral processes. Mass spectrometry analyses of …

Mass spectrometry measurements of neuropeptides: from identification to quantitation

EA De La Toba, SE Bell, EV Romanova… - Annual Review of …, 2022 - annualreviews.org
Neuropeptides (NPs), a unique class of neuronal signaling molecules, participate in a
variety of physiological processes and diseases. Quantitative measurements of NPs provide …

[HTML][HTML] Bsx is essential for differentiation of multiple neuromodulatory cell populations in the secondary prosencephalon

T Schredelseker, F Veit, RI Dorsky… - Frontiers in …, 2020 - frontiersin.org
The hypothalamus is characterized by great neuronal diversity, with many neuropeptides
and other neuromodulators being expressed within its multiple anatomical domains. The …

Complementary neuropeptide detection in crustacean brain by mass spectrometry imaging using formalin and alternative aqueous tissue washes

NQ Vu, AR Buchberger, J Johnson, L Li - Analytical and bioanalytical …, 2021 - Springer
Neuropeptides are low abundance signaling molecules that modulate almost every
physiological process, and dysregulation of neuropeptides is implicated in disease …