Preventing Parkinson's disease: an environmental agenda

BR De Miranda, SM Goldman… - Journal of …, 2022 - content.iospress.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Oxidative stress: major threat in traumatic brain injury

N Khatri, M Thakur, V Pareek, S Kumar… - CNS & Neurological …, 2018 - ingentaconnect.com
Background & Objective: Traumatic Brain Injury (TBI) is one of the major causes of mortality
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …

NRF2 as a therapeutic target in neurodegenerative diseases

MS Brandes, NE Gray - ASN neuro, 2020 - journals.sagepub.com
Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

A review of the molecular mechanisms of traumatic brain injury

AA Ladak, SA Enam, MT Ibrahim - World neurosurgery, 2019 - Elsevier
Traumatic brain injury (TBI) refers to any insult to the brain resulting in primary (direct) and
secondary (indirect) damage to the brain parenchyma. Secondary damage is often linked to …

Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities

D Lozano, GS Gonzales-Portillo, S Acosta… - Neuropsychiatric …, 2015 - Taylor & Francis
Traumatic brain injury (TBI) is a serious public health problem accounting for 1.4 million
emergency room visits by US citizens each year. Although TBI has been traditionally …

Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?

TA Henderson, LD Morries - Neuropsychiatric disease and …, 2015 - Taylor & Francis
Traumatic brain injury (TBI) is a growing health concern effecting civilians and military
personnel. Research has yielded a better understanding of the pathophysiology of TBI, but …

Pathophysiology associated with traumatic brain injury: current treatments and potential novel therapeutics

ML Pearn, IR Niesman, J Egawa, A Sawada… - Cellular and molecular …, 2017 - Springer
Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

Traumatic axonal injury: mechanisms and translational opportunities

CS Hill, MP Coleman, DK Menon - Trends in neurosciences, 2016 - cell.com
Traumatic axonal injury (TAI) is an important pathoanatomical subgroup of traumatic brain
injury (TBI) and a major driver of mortality and functional impairment. Experimental models …

Pathogenesis of brain edema and investigation into anti-edema drugs

S Michinaga, Y Koyama - International journal of molecular sciences, 2015 - mdpi.com
Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …

Neuroinflammation in animal models of traumatic brain injury

CC Chiu, YE Liao, LY Yang, JY Wang… - Journal of neuroscience …, 2016 - Elsevier
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide.
Neuroinflammation is prominent in the short and long-term consequences of neuronal …