Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription
to predominantly one parental allele. Since the discovery of the first long noncoding RNA …

Nuclear pore complexes (NPCs) are canonically known to regulate nucleocytoplasmic
transport. However, research efforts over the last decade have demonstrated that NPCs and …

Transposon (de) repression and heterochromatin reorganization are dynamically regulated
during cell fate determination and are hallmarks of cellular senescence. However, whether …

Stereotactic body radiotherapy (SBRT) has emerged as a standard treatment for non-small-
cell lung cancer. However, its therapeutic advantages are limited with the development of …

Master transcription factors such as TP63 establish super-enhancers (SEs) to drive core
transcriptional networks in cancer cells, yet the spatiotemporal regulation of SEs within the …

Acute myeloid leukemia (AML) represents 80% of adult leukemias and 15–20% of childhood
leukemias. AML are characterized by the presence of 20% blasts or more in the bone …

Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors
worldwide. Clinical success is suboptimal owing to late diagnosis, limited treatment options …

Nuclear pore complex (NPC)-mediated nucleocytoplasmic trafficking is essential for key
cellular processes, such as cell growth, cell differentiation, and gene regulation. The NPC …

The nuclear pore complex (NPC) is a massive nuclear envelope-embedded protein
complex, the canonical function of which is to mediate selective nucleocytoplasmic transport …

The polycomb repressive complexes 1 and 2 (PRCs; PRC1 and PRC2) are conserved
histone‐modifying enzymes that often function cooperatively to repress gene expression …