Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z Xiao, T Eng, A Mukhopadhyay… - Current Opinion in …, 2023 - Elsevier
Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …

Challenges and opportunities for engineered Escherichia coli as a pivotal chassis toward versatile tyrosine-derived chemicals production

SSW Effendi, IS Ng - Biotechnology Advances, 2023 - Elsevier
Growing concerns over limited fossil resources and associated environmental problems are
motivating the development of sustainable processes for the production of high-volume fuels …

Metabolic engineering of Vibrio natriegens for anaerobic succinate production

F Thoma, C Schulze, C Gutierrez‐Coto… - Microbial …, 2022 - Wiley Online Library
The biotechnological production of succinate bears serious potential to fully replace existing
petrochemical approaches in the future. In order to establish an economically viable …

[HTML][HTML] O-Acetyl-L-homoserine production enhanced by pathway strengthening and acetate supplementation in Corynebacterium glutamicum

N Li, W Zeng, J Zhou, S Xu - Biotechnology for Biofuels and Bioproducts, 2022 - Springer
Abstract Background O-Acetyl-L-homoserine (OAH) is an important potential platform
chemical. However, low levels of production of OAH are greatly limiting its industrial …

[HTML][HTML] Metabolic engineering of Corynebacterium glutamicum for acetate-based itaconic acid production

M Schmollack, F Werner, J Huber, D Kiefer… - … for Biofuels and …, 2022 - Springer
Background Itaconic acid is a promising platform chemical for a bio-based polymer industry.
Today, itaconic acid is biotechnologically produced with Aspergillus terreus at industrial …

[HTML][HTML] Metabolic engineering of Corynebacterium glutamicum for fatty alcohol production from glucose and wheat straw hydrolysate

F Werner, LS Schwardmann, D Siebert… - … for Biofuels and …, 2023 - Springer
Background Fatty acid-derived products such as fatty alcohols (FAL) find growing
application in cosmetic products, lubricants, or biofuels. So far, FAL are primarily produced …

Investigation of exopolysaccharide formation and its impact on anaerobic succinate production with Vibrio natriegens

C Schulze, M Hädrich, J Borger… - Microbial …, 2024 - Wiley Online Library
Vibrio natriegens is an emerging host for biotechnology due to its high growth and substrate
consumption rates. In industrial processes typically fed‐batch processes are applied to …

[HTML][HTML] A genome-reduced Corynebacterium glutamicum derivative discloses a hidden pathway relevant for 1,2-propanediol production

D Siebert, E Glawischnig, MT Wirth, M Vannahme… - Microbial Cell …, 2024 - Springer
Abstract Background 1, 2-propanediol (1, 2-PDO) is widely used in the cosmetic, food, and
drug industries with a worldwide consumption of over 1.5 million metric tons per year …

Escherichia coli aceE variants coding pyruvate dehydrogenase improve the generation of pyruvate‐derived acetoin

WC Moxley, RE Brown… - Engineering in Life …, 2023 - Wiley Online Library
Several chromosomally expressed AceE variants were constructed in Escherichia coli ΔldhA
ΔpoxB ΔppsA and compared using glucose as the sole carbon source. These variants were …

Improving growth properties of Corynebacterium glutamicum by implementing an iron‐responsive protocatechuate biosynthesis

F Thoma, C Appel, D Russ, J Huber… - Microbial …, 2023 - Wiley Online Library
Corynebacterium glutamicum experiences a transient iron limitation during growth in
minimal medium, which can be compensated by the external supplementation of …