Oxygenation, life, and the planetary system during Earth's middle history: An overview
The long history of life on Earth has unfolded as a cause-and-effect relationship with the
evolving amount of oxygen (O2) in the oceans and atmosphere. Oxygen deficiency …
evolving amount of oxygen (O2) in the oceans and atmosphere. Oxygen deficiency …
Coral reef survival under accelerating ocean deoxygenation
Global warming and local eutrophication simultaneously lower oxygen (O2) saturation and
increase biological O2 demands to cause deoxygenation. Tropical shallow waters, and their …
increase biological O2 demands to cause deoxygenation. Tropical shallow waters, and their …
Pharmacologic targeting of hypoxia-inducible factors
GL Semenza - Annual review of pharmacology and toxicology, 2019 - annualreviews.org
Hypoxia-inducible factors (HIFs) control transcriptional responses to reduced O2 availability.
HIFs are heterodimeric proteins composed of an O2-regulated HIF-α subunit and a …
HIFs are heterodimeric proteins composed of an O2-regulated HIF-α subunit and a …
Integrated records of environmental change and evolution challenge the Cambrian Explosion
Abstract The 'Cambrian Explosion'describes the rapid increase in animal diversity and
abundance, as manifest in the fossil record, between~ 540 and 520 million years ago (Ma) …
abundance, as manifest in the fossil record, between~ 540 and 520 million years ago (Ma) …
Targeting hypoxia-inducible factors: therapeutic opportunities and challenges
Hypoxia-inducible factors (HIFs) are highly conserved transcription factors that are crucial for
adaptation of metazoans to limited oxygen availability. Recently, HIF activation and …
adaptation of metazoans to limited oxygen availability. Recently, HIF activation and …
On the co‐evolution of surface oxygen levels and animals
Few topics in geobiology have been as extensively debated as the role of Earth's
oxygenation in controlling when and why animals emerged and diversified. All currently …
oxygenation in controlling when and why animals emerged and diversified. All currently …
[HTML][HTML] Highly fractionated chromium isotopes in Mesoproterozoic-aged shales and atmospheric oxygen
The history of atmospheric oxygen through the Mesoproterozoic Era is uncertain, but may
have played a role in the timing of major evolutionary developments among eukaryotes …
have played a role in the timing of major evolutionary developments among eukaryotes …
Global marine redox evolution from the late Neoproterozoic to the early Paleozoic constrained by the integration of Mo and U isotope records
The emergence and diversification of early animals is commonly thought to have coincided
with atmosphere and ocean oxygenation across the terminal Neoproterozoic and early …
with atmosphere and ocean oxygenation across the terminal Neoproterozoic and early …
Divergent expression of hypoxia response systems under deoxygenation in reef‐forming corals aligns with bleaching susceptibility
Exposure of marine life to low oxygen is accelerating worldwide via climate change and
localized pollution. Mass coral bleaching and mortality have recently occurred where reefs …
localized pollution. Mass coral bleaching and mortality have recently occurred where reefs …
Early animal evolution: a morphologist's view
C Nielsen - Royal Society open science, 2019 - royalsocietypublishing.org
Two hypotheses for the early radiation of the metazoans are vividly discussed in recent
phylogenomic studies, the 'Porifera-first'hypothesis, which places the poriferans as the sister …
phylogenomic studies, the 'Porifera-first'hypothesis, which places the poriferans as the sister …