Oxidative stress plays a crucial role in aging-related eye diseases, including age-related
macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative …

Of the 57 cytochrome P450 enzymes found in humans, at least 30 have ocular tissues as an
expression site. Yet knowledge of the roles of these P450s in the eye is limited, in part …

Tibetan sheep were introduced to the Qinghai Tibet plateau roughly 3,000 BP, making this
species a good model for investigating genetic mechanisms of high-altitude adaptation over …

Background Long-chain polyunsaturated fatty acids (LCPUFAs) and their metabolites are
closely related to neovascular eye diseases. However, the clinical significance of their …

Purpose: The purpose of this study was to explore the potential underlying mechanism of
anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist …

Appropriate nutrients are essential for cellular function. Dietary components can alter the risk
of systemic metabolic diseases, including cardiovascular diseases, cancer, diabetes, and …

Purpose: To determine whether genetic risk single nucleotide polymorphisms (SNPs) for
age-related macular degeneration (AMD) influence short-term response to intravitreal …