Circular RNA hsa_circ_0007990 as a blood biomarker for unruptured intracranial aneurysm with aneurysm wall enhancement

XB Wu, YT Wu, XX Guo, C Xiang, PS Chen… - Frontiers in …, 2022 - frontiersin.org
Background Circular RNAs (circRNAs) may involve the formation and rupture of intracranial
aneurysms (IA). Inflammation plays a vital role in the development and progression of IA …

High-dimensional immune profiling by mass cytometry revealed the circulating immune cell landscape in patients with intracranial aneurysm

P Ge, C Liu, L Chan, Y Pang, H Li, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Increasing evidence supports a critical role of chronic inflammation in
intracranial aneurysm (IA). Understanding how the immunological alterations in IA provides …

Transcriptomic studies on intracranial aneurysms

R Morga, J Pera - Genes, 2023 - mdpi.com
Intracranial aneurysm (IA) is a relatively common vascular malformation of an intracranial
artery. In most cases, its presence is asymptomatic, but IA rupture causing subarachnoid …

Profiling of circulating gene expression reveals molecular signatures associated with intracranial aneurysm rupture risk

KE Poppenberg, A Chien, BA Santo, L Chaves… - Molecular diagnosis & …, 2023 - Springer
Background Following detection, rupture risk assessment for intracranial aneurysms (IAs) is
critical. Towards molecular prognostics, we hypothesized that circulating blood RNA …

Dysregulated genes and signaling pathways in the formation and rupture of intracranial aneurysm

M Kumar, K Patel, S Chinnapparaj, T Sharma… - Translational Stroke …, 2023 - Springer
Intracranial aneurysm (IA) has the potential to rupture. Despite scientific advances, we are
still not in a position to screen patients for IA and identify those at risk of rupture. It is critical …

RNA expression signatures of intracranial aneurysm growth trajectory identified in circulating whole blood

KE Poppenberg, A Chien, BA Santo, AA Baig… - Journal of Personalized …, 2023 - mdpi.com
After detection, identifying which intracranial aneurysms (IAs) will rupture is imperative. We
hypothesized that RNA expression in circulating blood reflects IA growth rate as a surrogate …

Aberrant whole blood gene expression in the lumen of human intracranial aneurysms

VM Tutino, Y Lu, D Ishii, KE Poppenberg… - Diagnostics, 2021 - mdpi.com
The rupture of an intracranial aneurysm (IA) causes devastating hemorrhagic strokes. Yet,
most IAs remain asymptomatic and undetected until they rupture. In the search for circulating …

Web‐based transcriptome analysis determines a sixteen‐gene signature and associated drugs on hearing loss patients: A bioinformatics approach

M Lei, D Zhang, Y Sun, C Zou, Y Wang… - Journal of clinical …, 2021 - Wiley Online Library
Background Hearing loss is becoming more and more general. It may occur at all age and
affect the language learning ability of children and trigger serious social problems. Methods …

T Cells Immune Imbalance Present in Patients With Multiple Intracranial Aneurysms

C Tao, C Liu, P Ge, L Chan, Y Pang, J Li… - Clinical and …, 2024 - academic.oup.com
Growing evidence suggests that systemic immune and inflammatory responses may play a
critical role in the formation and development of aneurysms. Exploring the differences …

[HTML][HTML] Bioinformatics approach to analyse COVID-19 biomarkers accountable for generation of intracranial aneurysm in COVID-19 patients

M Snigdha, A Akter, M Al Amin, MZ Islam - Informatics in Medicine Unlocked, 2023 - Elsevier
COVID-19 became a health emergency on January 30, 2020. SARS-CoV-2 is the causative
agent of the coronavirus disease known as COVID-19 and can develop cardiometabolic and …