Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies
E Molinaro, C Romei, A Biagini, E Sabini… - Nature Reviews …, 2017 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …
2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association …
BR Haugen, EK Alexander, KC Bible, GM Doherty… - Thyroid, 2016 - liebertpub.com
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …
Genetic analysis of 779 advanced differentiated and anaplastic thyroid cancers
N Pozdeyev, LM Gay, ES Sokol, R Hartmaier… - Clinical Cancer …, 2018 - AACR
Purpose: To define the genetic landscape of advanced differentiated and anaplastic thyroid
cancer (ATC) and identify genetic alterations of potential diagnostic, prognostic, and …
cancer (ATC) and identify genetic alterations of potential diagnostic, prognostic, and …
Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
Lenvatinib versus placebo in radioiodine-refractory thyroid cancer
M Schlumberger, M Tahara, LJ Wirth… - … England Journal of …, 2015 - Mass Medical Soc
Background Lenvatinib, an oral inhibitor of vascular endothelial growth factor receptors 1, 2,
and 3, fibroblast growth factor receptors 1 through 4, platelet-derived growth factor receptor …
and 3, fibroblast growth factor receptors 1 through 4, platelet-derived growth factor receptor …
Pathogenesis of cancers derived from thyroid follicular cells
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
Molecular pathogenesis and mechanisms of thyroid cancer
M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …
understanding its molecular pathogenesis in recent years, as best exemplified by the …
Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer
M Xing, AS Alzahrani, KA Carson, YK Shong… - Journal of clinical …, 2015 - ascopubs.org
Purpose To investigate the prognostic value of BRAF V600E mutation for the recurrence of
papillary thyroid cancer (PTC). Patients and Methods This was a retrospective multicenter …
papillary thyroid cancer (PTC). Patients and Methods This was a retrospective multicenter …
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
Importance BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its
role in PTC-related patient mortality has not been established. Objective To investigate the …
role in PTC-related patient mortality has not been established. Objective To investigate the …
[HTML][HTML] Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to …
JM Oh, BC Ahn - Theranostics, 2021 - ncbi.nlm.nih.gov
The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …