Extracellular matrix remodeling in vascular disease: defining its regulators and pathological influence

PK Lin, GE Davis - Arteriosclerosis, Thrombosis, and Vascular …, 2023 - Am Heart Assoc
Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Changes in arterial stiffness in response to various types of exercise modalities: a narrative review on physiological and endothelial senescence perspectives

S Kresnajati, YY Lin, T Mündel, JR Bernard, HF Lin… - Cells, 2022 - mdpi.com
Arterial stiffness is a reliable independent predictor of cardiovascular events. Exercise
training might enhance arterial compliance through improved metabolic health status …

Resolvin E1/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II–Induced Hypertensive Mice

J Zhang, Z Yin, Y Xu, C Wei, S Peng, M Zhao, J Liu… - …, 2023 - Am Heart Assoc
BACKGROUND: Inflammation plays a critical role in the development of hypertension and
vascular remodeling. Resolvin E1 (RvE1), as one of the specialized proresolving lipid …

Galangin: A food‐derived flavonoid with therapeutic potential against a wide spectrum of diseases

D Wang, J Chen, L Pu, L Yu, F Xiong… - Phytotherapy …, 2023 - Wiley Online Library
Galangin is an important flavonoid with natural activity, that is abundant in galangal and
propolis. Currently, various biological activities of galangin have been disclosed, including …

Extracellular vesicles in vascular remodeling

C Ye, F Zheng, N Wu, G Zhu, X Li - Acta Pharmacologica Sinica, 2022 - nature.com
Vascular remodeling contributes to the development of a variety of vascular diseases
including hypertension and atherosclerosis. Phenotypic transformation of vascular cells …

Arterial remodeling: the role of mitochondrial metabolism in vascular smooth muscle cells

HL Qin, JH Bao, JJ Tang, DY Xu… - American Journal of …, 2023 - journals.physiology.org
Arterial remodeling is a common pathological basis of cardiovascular diseases such as
atherosclerosis, vascular restenosis, hypertension, pulmonary hypertension, aortic …

Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice

B Spronck, M Latorre, M Wang… - Journal of the …, 2021 - royalsocietypublishing.org
Hypertension induces significant aortic remodelling, often adaptive but sometimes not. To
identify immuno-mechanical mechanisms responsible for differential remodelling, we …

The adventitia in arterial development, remodeling, and hypertension

MW Majesky, MCM Weiser-Evans - Biochemical pharmacology, 2022 - Elsevier
The adventitia receives input signals from the vessel wall, the immune system, perivascular
nerves and from surrounding tissues to generate effector responses that regulate structural …

Aging effects on optic nerve neurodegeneration

J Coleman-Belin, A Harris, B Chen, J Zhou… - International Journal of …, 2023 - mdpi.com
Common risk factors for many ocular pathologies involve non-pathologic, age-related
damage to the optic nerve. Understanding the mechanisms of age-related changes can …

Hypertensive adults exhibit lower myelin content: a multicomponent relaxometry and diffusion magnetic resonance imaging study

JP Laporte, ME Faulkner, Z Gong, MABS Akhonda… - …, 2023 - Am Heart Assoc
BACKGROUND: It is unknown whether hypertension plays any role in cerebral myelination.
To fill this knowledge gap, we studied 90 cognitively unimpaired adults, age range 40 to 94 …