• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Objectives: There is growing recognition that high-quality care for patients and families in the
ICU requires exemplary interprofessional collaboration and communication. One important …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Abstract These European Resuscitation Council Ethics guidelines provide evidence-based
recommendations for the ethical, routine practice of resuscitation and end-of-life care of …

Background In relatives of patients dying in intensive care units (ICUs), inadequate team
support can increase the prevalence of prolonged grief and other psychological harm. We …

Importance End-of-life decisions occur daily in intensive care units (ICUs) around the world,
and these practices could change over time. Objective To determine the changes in end-of …

Importance For critically ill patients with advanced medical illnesses and poor prognoses,
overuse of invasive intensive care unit (ICU) treatments may prolong suffering without …

Importance Keeping a diary for patients while they are in the intensive care unit (ICU) might
reduce their posttraumatic stress disorder (PTSD) symptoms. Objectives To assess the effect …

Rationale: Family members of critically ill patients hospitalized in the intensive care unit
(ICU) often become caregivers, and they are at risk to develop adverse psychological …

Purpose The integration of palliative care into intensive care units (ICUs) is advocated to
mitigate physical and psychological burdens for patients and their families, and to improve …