Flowerbed-inspired biomimetic scaffold with rapid internal tissue infiltration and vascularization capacity for bone repair

X Zhou, Y Qian, L Chen, T Li, X Sun, X Ma, J Wang… - ACS …, 2023 - ACS Publications
The favorable microstructure and bioactivity of tissue-engineered bone scaffolds are closely
associated with the regenerative efficacy of bone defects. For the treatment of large bone …

Progress in self-healing hydrogels and their applications in bone tissue engineering

I Erezuma, I Lukin, M Desimone, YS Zhang… - Biomaterials …, 2023 - Elsevier
Bone tissue engineering (BTE) is constantly seeking novel treatments to address bone
injuries in all their varieties. It is necessary to find new ways to create structures that perfectly …

[HTML][HTML] Hydrogel drug delivery systems for bone regeneration

L Bai, G Tao, M Feng, Y Xie, S Cai, S Peng, J Xiao - Pharmaceutics, 2023 - mdpi.com
With the in-depth understanding of bone regeneration mechanisms and the development of
bone tissue engineering, a variety of scaffold carrier materials with desirable …

Glycopeptide‐Based Multifunctional Hydrogels Promote Diabetic Wound Healing through pH Regulation of Microenvironment

H Xia, Z Dong, Q Tang, R Ding, Y Bai… - Advanced functional …, 2023 - Wiley Online Library
Excessive inflammation, bacterial infection, and blocked angiogenesis make diabetic wound
healing challenging. Multifunctional wound dressings have several advantages in diabetic …

Remotely temporal scheduled macrophage phenotypic transition enables optimized immunomodulatory bone regeneration

D Huang, K Xu, X Huang, N Lin, Y Ye, S Lin, J Zhang… - Small, 2022 - Wiley Online Library
Precise timing of macrophage polarization plays a pivotal role in immunomodulation of
tissue regeneration, yet most studies mainly focus on M2 macrophages for their anti …

Bioinspired piezoelectric periosteum to augment bone regeneration via synergistic immunomodulation and osteogenesis

H Liu, Y Shi, Y Zhu, P Wu, Z Deng, Q Dong… - … Applied Materials & …, 2023 - ACS Publications
Ideal periosteum materials are required to participate in a sequence of bone repair-related
physiological events, including the initial immune response, endogenous stem cell …

Mild Photothermal‐Stimulation Based on Injectable and Photocurable Hydrogels Orchestrates Immunomodulation and Osteogenesis for High‐Performance Bone …

M Wu, H Liu, Y Zhu, F Chen, Z Chen, L Guo, P Wu, G Li… - Small, 2023 - Wiley Online Library
A photoactivated bone scaffold integrated with minimally invasive implantation and mild
thermal‐stimulation capability shows great promise in the repair and regeneration of …

Bio-inspired glycosylated nano-hydroxyapatites enhance endogenous bone regeneration by modulating macrophage M2 polarization

D Qiao, S Cheng, Z Xing, Q Zhang, S Song, F Yan… - Acta Biomaterialia, 2023 - Elsevier
A macrophage-associated immune response is vital in bone regeneration. Mannose
receptor (MR), a macrophage pattern-recognition receptor, is crucial for the maintenance of …

nHA-loaded gelatin/alginate hydrogel with combined physical and bioactive features for maxillofacial bone repair

X Zhou, J Sun, K Wo, H Wei, H Lei, J Zhang, X Lu… - Carbohydrate …, 2022 - Elsevier
Critical-sized maxillofacial bone defects have been a tough clinical challenge considering
their requirements for functional and structural repair. In this study, an injectable in-situ …

Bifunctional hydrogel-integrated 3D printed scaffold for repairing infected bone defects

Q Zhang, X Zhou, H Du, Y Ha, Y Xu… - … Biomaterials Science & …, 2023 - ACS Publications
The clinical treatment of infectious bone defects is difficult and time-consuming due to the
coexistence of infection and bone defects, and the simultaneous control of infection and …