From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning

LS Li, L Yang, L Zhuang, ZY Ye, WG Zhao… - Military Medical …, 2023 - Springer
Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …

Mechanisms of lung damage in tuberculosis: implications for chronic obstructive pulmonary disease

A Kayongo, B Nyiro, T Siddharthan… - Frontiers in Cellular …, 2023 - frontiersin.org
Pulmonary tuberculosis is increasingly recognized as a risk factor for COPD. Severe lung
function impairment has been reported in post-TB patients. Despite increasing evidence to …

Research progress of single-cell sequencing in tuberculosis

J Pan, Z Chang, X Zhang, Q Dong, H Zhao… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis is a major infectious disease caused by Mycobacterium tuberculosis infection.
The pathogenesis and immune mechanism of tuberculosis are not clear, and it is urgent to …

Single-Cell Transcriptomics of Mtb/HIV Co-Infection

S Kulkarni, JJ Endsley, Z Lai, T Bradley, R Sharan - Cells, 2023 - mdpi.com
Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) co-infection continues to pose
a significant healthcare burden. HIV co-infection during TB predisposes the host to the …

Single‐cell sequencing: Current applications in various tuberculosis specimen types

Y Zeng, Q Ma, J Chen, X Kong, Z Chen, H Liu… - Cell …, 2024 - Wiley Online Library
Tuberculosis (TB) is a chronic disease caused by Mycobacterium tuberculosis (M. tb) and
responsible for millions of deaths worldwide each year. It has a complex pathogenesis that …

Comprehensive Analysis of Immune Cell Infiltration and M2-Like Macrophage Biomarker Expression Patterns in Atrial Fibrillation

M Yang, X Xu, X Zhao, Y Ge, J Qin… - … Journal of General …, 2024 - Taylor & Francis
Background Macrophages play a crucial role in the progression of AF, closely linked to atrial
inflammation and myocardial fibrosis. However, the functions and molecular mechanisms of …

Predictive biomarkers for latent Mycobacterium tuberculosis infection

H Singh, N Gonzalez-Juarbe, R Pieper, Y Yu… - Tuberculosis, 2024 - Elsevier
Tuberculosis is a leading cause of infectious death worldwide, with almost a fourth of the
world's population latently infected with its causative agent, Mycobacterium tuberculosis …

Macrophage-Secreted Exosomal HCG11 Promotes Autophagy in Antigen 85B-Infected Macrophages and Inhibits Fibroblast Fibrosis to Affect Tracheobronchial …

L Zhou, L Luo, L Luo, Y Ding, Z Lu… - Journal of Biomedical …, 2022 - ingentaconnect.com
Background: Tracheobronchial tuberculosis (TBTB) is a serious threat to human health. We
aimed to explore the potential regulatory mechanism by which macrophages secrete …