Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

The global prevalence of diabetes continues to increase partly due to rapid urbanization and
an increase in the aging population. Consequently, this is associated with a parallel …

Aims Diabetic retinopathy (DR) can cause vision loss in patients with diabetes. The present
study evaluated the expression of thioredoxin interacting protein (TXNIP) and investigated …

Backgrounds: Doxorubicin (Dox) is a classical antitumor antibiotic widely restricted for use
due to its cardiotoxicity. Daidzein (Daid) is a soy isoflavone that enhances antioxidant …

Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic proteins
and organelles, which realizes the metabolic needs of cells and the renewal of organelles …

Our previous data confirmed that 1, 8-Cineole had an antihypertensive effect in animal
models. However, it is unclear whether antihypertension is dependent on the protective …

Diabetes (DB) is a risk factor for osteoarthritis progression. High glucose (HG) is one of the
key pathological features of DB and has been demonstrated to induce apoptosis and …

Cardiovascular disease (CVD) remains the leading cause of death worldwide. Therefore,
exploring the mechanism of CVDs and critical regulatory factors is of great significance for …

Background Cardiac hypertrophy (CH) is a well‐established risk factor for many
cardiovascular diseases and a primary cause of mortality and morbidity among older adults …

It is reported that Notch3 and mTOR signaling pathways are involved in autophagy, and both
can be activated by high glucose (HG). However, the relationship between Notch3 and …