ATP and adenosine metabolism in cancer: exploitation for therapeutic gain

GG Yegutkin, D Boison - Pharmacological reviews, 2022 - ASPET
Adenosine is an evolutionary ancient metabolic regulator linking energy state to physiologic
processes, including immunomodulation and cell proliferation. Tumors create an adenosine …

Single cell protein: A potential substitute in human and animal nutrition

BC Bratosin, S Darjan, DC Vodnar - Sustainability, 2021 - mdpi.com
Single cell protein (SCP) is the first product of the fermentation process and has proven to be
a good protein alternative. Food competition is becoming more intense as the world's …

Targeting tumor microenvironment using tumor-infiltrating lymphocytes as therapeutics against tumorigenesis

H Qayoom, S Sofi, MA Mir - Immunologic research, 2023 - Springer
The immune system plays a vital role in suppressing tumor cell progression. The tumor
microenvironment augmented with significant levels of tumor-infiltrating lymphocytes has …

Discovering untapped microbial communities through metagenomics for microplastic remediation: recent advances, challenges, and way forward

AK Wani, N Akhtar, N Naqash, F Rahayu… - … Science and Pollution …, 2023 - Springer
Microplastics (MPs) are ubiquitous pollutants persisting almost everywhere in the
environment. With the increase in anthropogenic activities, MP accumulation is increasing …

The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex

Z Guan, J Chen, R Liu, Y Chen, Q Xing, Z Du… - Nature …, 2023 - nature.com
Inorganic polyphosphate (polyP) is an ancient energy metabolite and phosphate store that
occurs ubiquitously in all organisms. The vacuolar transporter chaperone (VTC) complex …

Alkaline phosphatase: a reliable endogenous partner for drug delivery and diagnostics

B Le‐Vinh, ZB Akkuş‐Dağdeviren… - Advanced …, 2022 - Wiley Online Library
Since the 1960s the membrane‐bound enzyme alkaline phosphatase (ALP) has been
utilized in drug delivery. As it cleaves phosphate substructures from drugs, auxiliary agents …

[HTML][HTML] Polyphosphate-crosslinked collagen scaffolds for hemostasis and alveolar bone regeneration after tooth extraction

J Gu, K Jiao, J Li, J Yan, K Wang, F Wang, Y Liu… - Bioactive materials, 2022 - Elsevier
Post-extraction bleeding and alveolar bone resorption are the two frequently encountered
complications after tooth extraction that result in poor healing and rehabilitation difficulties …

Using marimo as a nature-derived microalgal-bacterial granular consortium for municipal wastewater treatment

P Sun, B Ji - Chemical Engineering Journal, 2023 - Elsevier
The photo-driven biological wastewater treatment processes based on the microalgae-
bacteria symbioses or bio-granules have gained accelerated interest under the era of …

History of ectonucleotidases and their role in purinergic signaling

H Zimmermann - Biochemical Pharmacology, 2021 - Elsevier
Ectonucleotidases are key for purinergic signaling. They control the duration of activity of
purinergic receptor agonists. At the same time, they produce hydrolysis products as …

The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations

M Neufurth, X Wang, E Tolba, I Lieberwirth… - Biochemical …, 2020 - Elsevier
Inorganic polyphosphate (polyP) is a morphogenetically active and metabolic energy-
delivering physiological polymer that is released from blood platelets. Here, we show that …