[HTML][HTML] A Compressive Review about Taxol®: History and Future Challenges

J Gallego-Jara, G Lozano-Terol, RA Sola-Martínez… - Molecules, 2020 - mdpi.com
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

[HTML][HTML] Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review

FT Borsoi, IA Neri-Numa, WQ de Oliveira… - Food Chemistry …, 2023 - Elsevier
Abstract Chronic Non-Communicable Diseases (NCDs) have been considered a global
health problem, characterized as diseases of multiple factors, which are developed …

[HTML][HTML] Susceptibility of cervical cancer to dihydroartemisinin-induced ferritinophagy-dependent ferroptosis

H Shi, L Xiong, G Yan, S Du, J Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
The clinical therapeutics of cervical cancer is limited due to the drug resistance and
metastasis of tumor. As a novel target for antitumor therapy, ferroptosis is deemed to be …

[HTML][HTML] Genistein as a regulator of signaling pathways and microRNAs in different types of cancers

Z Javed, K Khan, J Herrera-Bravo, S Naeem… - Cancer Cell …, 2021 - Springer
Cancers are complex diseases orchestrated by a plethora of extrinsic and intrinsic factors.
Research spanning over several decades has provided better understanding of complex …

[HTML][HTML] Disease-associated regulation of non-coding RNAs by resveratrol: molecular insights and therapeutic applications

R Giordo, Z Wehbe, AM Posadino, GL Erre… - Frontiers in Cell and …, 2022 - frontiersin.org
There have been significant advances, particularly over the last 20 years, in the identification
of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease …

Highly sensitive and facile microRNA detection based on target triggered exponential rolling-circle amplification coupling with CRISPR/Cas12a

S Zhou, H Sun, J Dong, P Lu, L Deng, Y Liu… - Analytica Chimica …, 2023 - Elsevier
MicroRNAs (miRNAs) play a crucial role in the regulation of gene expression and have been
implicated in many diseases. Herein, we develop a target triggered exponential rolling-circle …

[HTML][HTML] Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention

MA Rahman, MDH Rahman, MS Hossain, P Biswas… - Biomedicines, 2020 - mdpi.com
Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …

[HTML][HTML] Pinostrobin, a fingerroot compound, regulates miR-181b-5p and induces acute leukemic cell apoptosis

C Norkaew, P Subkorn, C Chatupheeraphat… - Scientific Reports, 2023 - nature.com
Pinostrobin (PN) is the most abundant flavonoid found in fingerroot. Although the anti-
leukemic properties of PN have been reported, its mechanisms are still unclear. MicroRNAs …

[HTML][HTML] The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer

J Huang, W Zhou, C Hao, Q He, X Tu - PLoS Genetics, 2022 - journals.plos.org
Background Bladder cancer (BCa) is one of the most prevalent malignancies globally.
Previous study has reported the inhibitory effect of methyltransferase-like 14 (METTL14) on …

[HTML][HTML] Pinostrobin induces acute leukemia cell apoptosis via the regulation of miR-410-5p and SFRP5

C Norkaew, S Roytrakul, S Charoenlappanit… - Life Sciences, 2023 - Elsevier
Aims This study attempted to explore the mechanisms involved in pinostrobin (PN)-mediated
acute leukemia cell apoptosis regulated by miR-410-5p. Material and methods NB4 and …