[HTML][HTML] A Compressive Review about Taxol®: History and Future Challenges
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
[HTML][HTML] Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review
FT Borsoi, IA Neri-Numa, WQ de Oliveira… - Food Chemistry …, 2023 - Elsevier
Abstract Chronic Non-Communicable Diseases (NCDs) have been considered a global
health problem, characterized as diseases of multiple factors, which are developed …
health problem, characterized as diseases of multiple factors, which are developed …
[HTML][HTML] Susceptibility of cervical cancer to dihydroartemisinin-induced ferritinophagy-dependent ferroptosis
H Shi, L Xiong, G Yan, S Du, J Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
The clinical therapeutics of cervical cancer is limited due to the drug resistance and
metastasis of tumor. As a novel target for antitumor therapy, ferroptosis is deemed to be …
metastasis of tumor. As a novel target for antitumor therapy, ferroptosis is deemed to be …
[HTML][HTML] Genistein as a regulator of signaling pathways and microRNAs in different types of cancers
Cancers are complex diseases orchestrated by a plethora of extrinsic and intrinsic factors.
Research spanning over several decades has provided better understanding of complex …
Research spanning over several decades has provided better understanding of complex …
[HTML][HTML] Disease-associated regulation of non-coding RNAs by resveratrol: molecular insights and therapeutic applications
There have been significant advances, particularly over the last 20 years, in the identification
of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease …
of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease …
Highly sensitive and facile microRNA detection based on target triggered exponential rolling-circle amplification coupling with CRISPR/Cas12a
S Zhou, H Sun, J Dong, P Lu, L Deng, Y Liu… - Analytica Chimica …, 2023 - Elsevier
MicroRNAs (miRNAs) play a crucial role in the regulation of gene expression and have been
implicated in many diseases. Herein, we develop a target triggered exponential rolling-circle …
implicated in many diseases. Herein, we develop a target triggered exponential rolling-circle …
[HTML][HTML] Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention
Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
[HTML][HTML] Pinostrobin, a fingerroot compound, regulates miR-181b-5p and induces acute leukemic cell apoptosis
C Norkaew, P Subkorn, C Chatupheeraphat… - Scientific Reports, 2023 - nature.com
Pinostrobin (PN) is the most abundant flavonoid found in fingerroot. Although the anti-
leukemic properties of PN have been reported, its mechanisms are still unclear. MicroRNAs …
leukemic properties of PN have been reported, its mechanisms are still unclear. MicroRNAs …
[HTML][HTML] The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer
J Huang, W Zhou, C Hao, Q He, X Tu - PLoS Genetics, 2022 - journals.plos.org
Background Bladder cancer (BCa) is one of the most prevalent malignancies globally.
Previous study has reported the inhibitory effect of methyltransferase-like 14 (METTL14) on …
Previous study has reported the inhibitory effect of methyltransferase-like 14 (METTL14) on …
[HTML][HTML] Pinostrobin induces acute leukemia cell apoptosis via the regulation of miR-410-5p and SFRP5
C Norkaew, S Roytrakul, S Charoenlappanit… - Life Sciences, 2023 - Elsevier
Aims This study attempted to explore the mechanisms involved in pinostrobin (PN)-mediated
acute leukemia cell apoptosis regulated by miR-410-5p. Material and methods NB4 and …
acute leukemia cell apoptosis regulated by miR-410-5p. Material and methods NB4 and …