[HTML][HTML] The 5-HT1B receptor - a potential target for antidepressant treatment

M Tiger, K Varnäs, Y Okubo, J Lundberg - Psychopharmacology, 2018 - Springer
Major depressive disorder (MDD) is the leading cause of disability worldwide. The serotonin
hypothesis may be the model of MDD pathophysiology with the most support. The majority of …

An AOP analysis of selective serotonin reuptake inhibitors (SSRIs) for fish

MD McDonald - Comparative Biochemistry and Physiology Part C …, 2017 - Elsevier
Pharmaceuticals and personal care products (PPCPs) are found in measureable quantities
within the aquatic environment. Selective serotonin reuptake inhibitor (SSRI) …

Effect of social isolation on anxiety-related behaviors, cortisol, and monoamines in adult zebrafish.

S Shams, D Seguin, A Facciol, D Chatterjee… - Behavioral …, 2017 - psycnet.apa.org
Social isolation can be used to study behavioral, neural, and hormonal mechanisms that
regulate interactions in social animals. Although isolation effects have been reported in …

Comparison of the chronic toxicities of graphene and graphene oxide toward adult zebrafish by using biochemical and phenomic approaches

G Audira, JS Lee, P Siregar, N Malhotra… - Environmental …, 2021 - Elsevier
Graphene (GR) and graphene oxide (GO) are widely being used as promising candidates
for biomedical applications, as well as for bio-sensing, drug delivery, and anticancer …

Neurochemical and behavioral responses to unpredictable chronic mild stress following developmental isolation: the zebrafish as a model for major depression

N Fulcher, S Tran, S Shams, D Chatterjee, R Gerlai - Zebrafish, 2017 - liebertpub.com
Unpredictable chronic mild stress (UCMS) and developmental social isolation are often
utilized in laboratory animals to mimic unpredictable life stressors and early life adversity …

Generation-specific and interactive effects of pesticide and antidepressant exposure in a fish model call for multi-stressor and multigenerational testing

ESJ Thoré, F Van Hooreweghe, C Philippe… - Aquatic Toxicology, 2021 - Elsevier
Ecological risks of a pollutant are typically assessed via short-term exposure of model
organisms to that single compound. Such tests are informative, but cannot ascertain effects …

Maerua angolensis stem bark extract reverses anxiety and related behaviours in zebrafish—Involvement of GABAergic and 5-HT systems

CK Benneh, RP Biney, PK Mante, A Tandoh… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Maerua angolensis DC (Capparaceae) has been
employed in the management of several central nervous system (CNS) disorders including …

[HTML][HTML] Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure

H Yang, X Liang, Y Zhao, X Gu, Z Mao, Q Zeng… - Ecotoxicology and …, 2021 - Elsevier
Sertraline (SER) is one of the most frequently detected antidepressant drugs in aquatic
environments. However, knowledge regarding SER-induced behavioral alterations in fish is …

[HTML][HTML] High-resolution tracking of unconfined zebrafish behavior reveals stimulatory and anxiolytic effects of psilocybin

D Braun, AM Rosenberg, E Rabaniam, R Haruvi… - Molecular …, 2024 - nature.com
Serotonergic psychedelics are emerging therapeutics for psychiatric disorders, yet their
underlying mechanisms of action in the brain remain largely elusive. Here, we developed a …

[HTML][HTML] Protein fraction from Artocarpus altilis pulp exhibits antioxidant properties and reverses anxiety behavior in adult zebrafish via the serotoninergic system

NGG Gonçalves, JIF de Araújo, FEA Magalhães… - Journal of functional …, 2020 - Elsevier
Breadfruit (Artocarpus altilis) is a staple food in tropical regions and has several uses. The
aim of this study was to establish the nutraceutical potential of an enriched protein fraction of …