[HTML][HTML] Brief developmental exposure to fluoxetine causes life-long alteration of the brain transcriptome in zebrafish

A Nozari, R Gagné, C Lu, C Yauk… - Frontiers in …, 2022 - frontiersin.org
Fluoxetine (FLX) and other selective serotonin reuptake inhibitors are widely used to treat
depressive disorders during pregnancy. Early-life exposure to FLX is known to disrupt the …

Synthesis and anxiolytic effect of europium metallic complex containing lapachol [Eu (DBM) 3. LAP] in adult zebrafish through serotonergic neurotransmission: in vivo …

JFS de Menezes, AM Sá Pires Silva… - Journal of …, 2024 - Taylor & Francis
Anxiety-related mental health problems are estimated at 3.6% globally, benzodiazepines
(BZDs) are the class of drugs indicated for the treatment of anxiety, including lorazepam and …

[HTML][HTML] 神经递质5-羟色胺(5-HT) 及其受体对鱼类行为和生理影响的研究进展

李海霞, 刘鹰, 张旭, 王婕, 胡雨, 马真 - 大连海洋大学学报, 2022 - xuebao.dlou.edu.cn
随着养殖智能化水平的提高和鱼类福利关注度的提升, 对养殖条件下鱼类生理和行为的研究日益
受到重视. 5-羟色胺(5-hydroxy tryptamine, 5-HT) 是一种广泛存在于大脑和外周组织中的抑制性 …

The serotonin transporter and nonselective transporters are involved in peripheral serotonin uptake in the Gulf toadfish, Opsanus beta

MHB Amador, MD McDonald - American Journal of …, 2018 - journals.physiology.org
In mammals, circulating serotonin [5-hydroxytryptamine (5-HT)] is sequestered by platelets
via the 5-HT transporter (SERT) to prevent unintended signaling by this potent signaling …

Role of 5-hydroxytryptamine type 3 receptors in the regulation of anxiety reactions

Y Du, Z Li, Y Zhao, J Han, W Hu, Z Liu - Journal of Zhejiang University …, 2024 - Springer
Hydroxytryptamine (5-HT) type 3 receptor (5-HT3R) is the only type of ligand-gated ion
channel in the 5-HT receptor family. Through the high permeability of Na+, K+, and Ca2+ …

Synthesis, molecular docking, ADMET, and evaluation of the anxiolytic effect in adult zebrafish of synthetic chalcone (E)‐3‐(4‐(dimethylamino)phenyl)‐1‐(2 …

L Santos Oliveira… - Fundamental & …, 2024 - Wiley Online Library
Background Anxiety disorders represent the complex interaction between biological,
psychological, temperamental, and environmental factors; drugs available to treat anxiety …

5-羟色胺3 受体对焦虑反应的调节作用

Y DU, Z LI, Y ZHAO, J HAN, W HU, Z LIU… - Journal of Zhejiang …, 2024 - jzus.zju.edu.cn
5-羟色胺3 受体(5-hydroxytryptamine type 3 receptor, 5-HT 3 R) 是5-羟色胺受体家族中唯一的
一类配体门控离子通道, 通过对Na+, K+, Ca 2+ 等离子的高通透性以及继发性电压门控Ca 2+ …

Zebrafish are able to detect ethanol in their environment

S Tran, H Chow, B Tsang, A Facciol, P Gandhi, P Desai… - Zebrafish, 2017 - liebertpub.com
Zebrafish have become a popular animal model for studying the development of alcohol
addiction. Several behavioral paradigms for studying alcohol addiction have been …

Home tank water versus novel water differentially affect alcohol-induced locomotor activity and anxiety related behaviours in zebrafish

S Tran, A Facciol, R Gerlai - Pharmacology Biochemistry and Behavior, 2016 - Elsevier
The zebrafish may be uniquely well suited for studying alcohol's mechanisms of action in
vivo, since alcohol can be administered via immersion in a non-invasive manner. Despite …

Anxiolytic effects of N-(4,5-dihydro-5-oxo-1,2-dithiolo-[4,3,b]-pyrrole-6-yl)-N-methylformamide, a pyrroloformamide isolated from a marine Streptomyces sp., in adult …

HPSF Cesário, FCO Silva, MKA Ferreira… - Journal of …, 2024 - Taylor & Francis
General anxiety disorders are among the most prevalent mental health problems worldwide.
The emergence and development of anxiety disorders can be due to genetic (30–50%) or …