[HTML][HTML] Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
Culture of cells using various microfluidic devices is becoming more common within
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
From 3D cell culture to organs-on-chips
3D cell-culture models have recently garnered great attention because they often promote
levels of cell differentiation and tissue organization not possible in conventional 2D culture …
levels of cell differentiation and tissue organization not possible in conventional 2D culture …
Reconstituting organ-level lung functions on a chip
D Huh, BD Matthews, A Mammoto, M Montoya-Zavala… - Science, 2010 - science.org
Here, we describe a biomimetic microsystem that reconstitutes the critical functional alveolar-
capillary interface of the human lung. This bioinspired microdevice reproduces complex …
capillary interface of the human lung. This bioinspired microdevice reproduces complex …
Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics
This article reviews acoustic microfluidics: the use of acoustic fields, principally ultrasonics,
for application in microfluidics. Although acoustics is a classical field, its promising, and …
for application in microfluidics. Although acoustics is a classical field, its promising, and …
2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …
[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation
S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …
industry. However, animal welfare protection and other shortcomings of traditional drug …
Recent progress in translational engineered in vitro models of the central nervous system
The complexity of the human brain poses a substantial challenge for the development of
models of the CNS. Current animal models lack many essential human characteristics (in …
models of the CNS. Current animal models lack many essential human characteristics (in …
Cell-based biosensors and their application in biomedicine
A biosensor is an analytical device that can be used for detecting analytes and combines a
biological component with a physicochemical detecting transducer. In recent years …
biological component with a physicochemical detecting transducer. In recent years …
Microfluidic devices for bioapplications
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …