Intersections between regulated cell death and autophagy
In multicellular organisms, cell death is an essential aspect of life. Over the past decade, the
spectrum of different forms of regulated cell death (RCD) has expanded dramatically with …
spectrum of different forms of regulated cell death (RCD) has expanded dramatically with …
Clinical relevance of sperm DNA damage in assisted reproduction
N Tarozzi, D Bizzaro, C Flamigni, A Borini - Reproductive BioMedicine …, 2007 - Elsevier
Many studies have shown how a 'paternal effect'can cause repeated assisted reproduction
failures. In particular, with increasing experience of intracytoplasmic sperm injection (ICSI), it …
failures. In particular, with increasing experience of intracytoplasmic sperm injection (ICSI), it …
Lactate inhibits germ cell apoptosis in the human testis
K Erkkilä, H Aito, K Aalto, V Pentikäinen… - Molecular human …, 2002 - academic.oup.com
Dysregulation of male germ cell apoptosis has been associated with the pathogenesis of
male infertility. Therefore, factors involved in the regulation of germ cell death are being …
male infertility. Therefore, factors involved in the regulation of germ cell death are being …
Caspase-3 and caspase-activated deoxyribonuclease are associated with testicular germ cell apoptosis resulting from reduced intratesticular testosterone
JM Kim, SR Ghosh, ACP Weil, BR Zirkin - Endocrinology, 2001 - academic.oup.com
The purpose of the present study was to examine the possible involvement of caspase-3
and caspase-activated deoxyribonuclease in rat testicular germ cell apoptosis resulting from …
and caspase-activated deoxyribonuclease in rat testicular germ cell apoptosis resulting from …
[HTML][HTML] Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection
E Bjanes, RG Sillas, R Matsuda, B Demarco… - PLoS …, 2021 - journals.plos.org
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory
caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates …
caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates …
The relevance of spontaneous-and chemically-induced alterations in testicular germ cell apoptosis to toxicology
JH Richburg - Toxicology letters, 2000 - Elsevier
Elimination of germ cells via apoptosis occurs spontaneously under normal physiologic
conditions and is often heightened after chemical-induced testicular injury. Though many …
conditions and is often heightened after chemical-induced testicular injury. Though many …
Stem cell factor protects germ cells from apoptosis in vitro
Stem cell factor (SCF) plays an important role in migration, adhesion, proliferation, and
survival of primordial germ cells and spermatogonia during testicular development …
survival of primordial germ cells and spermatogonia during testicular development …
The role of the Fas/FasL signaling pathway in environmental toxicant-induced testicular cell apoptosis: An update
M Wang, P Su - Systems biology in reproductive medicine, 2018 - Taylor & Francis
ABSTRACT The Fas/FasL signaling pathway is one of the major pathways that regulate
apoptosis. Increasing studies have shown that the activation of the Fas/FasL signaling …
apoptosis. Increasing studies have shown that the activation of the Fas/FasL signaling …
Specific arrests of spermatogenesis in genetically modified and mutant mice.
DG De Rooij, P De Boer - Cytogenetic & Genome Research, 2003 - karger.com
In naturally occurring mutant mice but also in mice genetically modified for the study of other
organs, relatively often a spermatogenic arrest is seen. In a number of cases the arrests …
organs, relatively often a spermatogenic arrest is seen. In a number of cases the arrests …
Evidence of acrylamide-and glycidamide-induced oxidative stress and apoptosis in Leydig and Sertoli cells
Acrylamide (AA) is a common chemical, produced during food processing and widely used
in various industries and laboratory processes. Thus, AA causes a significant risk for human …
in various industries and laboratory processes. Thus, AA causes a significant risk for human …