Background Spermatogenesis is an intricate developmental process during which
undifferentiated spermatogonia, containing spermatogonial stem cells (SSCs), undergo self …

Spermatogenesis is a prolonged and highly ordered physiological process that produces
haploid male germ cells through more than 40 steps and experiences dramatic …

Vinclozolin is a systemic dicarboximide fungicide that is used on fruits, vegetables,
ornamental plants, and turf grass. Vinclozolin and its metabolites are known to be endocrine …

Obesity has become a global pandemic since the last few decades with prevalence in more
than one-third of the population in the United States. Another concurrent global health …

Sertoli and germ cell interactions are essential for spermatogenesis and, thus, male fertility.
Sertoli cells provide a specialized microenvironment for spermatogonial stem cells to divide …

This review examines experimental models of Sertoli cell injury resulting in germ cell
apoptosis. Since germ cells exist in an environment created by Sertoli cells, paracrine …

The purpose of this review is to describe how the immune cells present in the testis interact
with the germinal epithelium contributing to survival or apoptosis of germ cells (GCs) …

Here we investigated a pharmacological approach to inhibit spermatogenesis in the mouse
model by manipulating retinoid signaling using low doses of the pan-retinoic acid receptor …

In both flies and mammals, almost one-third of the newly emerging male germ cells are
spontaneously eliminated before entering meiosis. Here, we show that in Drosophila, germ …

Bcl-w, a prosurvival member of the Bcl-2 family, is essential for spermatogenesis. However,
the mechanisms by which Bcl-w participates in the regulation of apoptosis in the testis are …