Historically, the precursor cells to spermatogonia have been identified as “gonocytes,” a
term created in the fifties to encompass fetal and neonatal germ cells from the time they …

In this study, isolated spermatogonial stem cells (SSCs) and Sertoli cells using enzymatic
digestion from patients with maturation arrest of spermatogenesis were grown in Dulbecco's …

Members of the Bcl-2 protein family fall into two categories on the basis of their ability to
either promote or suppress apoptosis. Recent findings have linked these proteins to …

The present study investigates the molecular apoptotic pathway in germ cells following
acute ischemia of the rat testis. Rats were subjected to ischemia-inducing torsion and testes …

It is obvious that natural selection operates at the level of individuals and collections of
individuals. Nearly two decades ago we showed that in multi-individual colonies of …

Background Sperm DNA integrity is of paramount importance in the prognosis of fertility. We
applied image cytometry to a toluidine blue (TB) test we recently proposed. Methods Sperm …

Introduction: Sperm DNA damage is the major molecular cause of male infertility, which has
a negative effect on reproductive outcomes in couples. Sperm DNA damage originates …

Adrenarche is an endocrine developmental process whereby humans and select nonhuman
primates increase adrenal output of a series of steroids, especially dehydroepiandrosterone …

Spermatogonial stem cells are a self-renewing population of adult stem cells capable of 20
producing progeny cells for sperm production throughout the life of the male. Regulation 21 …

Abstract CUG-BP1/CELF1 is a multifunctional RNA-binding protein involved in the
regulation of alternative splicing and translation. To elucidate its role in mammalian …