Dendritic cells (DCs) control innate and adaptive immunity by patrolling tissues to gather
antigens and danger signals derived from microbes and tissue. Subsequently, DCs integrate …

It is being increasingly acknowledged that immune cells depend on certain metabolic traits
to perform their functions and that the extracellular environment can influence cell …

T cell subsets including effector (T eff), regulatory (T reg), and memory (T mem) cells are
characterized by distinct metabolic profiles that influence their differentiation and function …

Macrophages undergo metabolic changes during activation that are coupled to functional
responses. The gram negative bacterial product lipopolysaccharide (LPS) is especially …

Acetyl-CoA carboxylase (ACC) regulates lipid synthesis; however, its role in inflammatory
regulation in macrophages remains unclear. We generated mice that are deficient in both …

Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …

New complexes of zinc (II) and copper (II) with 2-furoic acid (Hfur), acetic acids and N-donor
ligands with the compositions [Zn2 (fur) 4] n (1),[Zn2 (fur) 4 (NH2py) 2](2, NH2py= 3 …

CD 8+ T cells are key members of the adaptive immune response against infections and
cancer. As we discuss in this review, these cells can present diverse metabolic …

Systemic lupus erythematosus (SLE) is a heterogeneous disease characterized by the
production of abnormal autoantibodies and immune complexes that can affect the organ and …

Studies over the past decade have revealed that metabolism profoundly influences immune
responses. In particular, metabolism causes epigenetic regulation of gene expression, as a …