Metabolic control of dendritic cell functions: digesting information
Dendritic cells (DCs) control innate and adaptive immunity by patrolling tissues to gather
antigens and danger signals derived from microbes and tissue. Subsequently, DCs integrate …
antigens and danger signals derived from microbes and tissue. Subsequently, DCs integrate …
Metabolic programming in dendritic cells tailors immune responses and homeostasis
SH Møller, L Wang, PC Ho - Cellular & molecular immunology, 2022 - nature.com
It is being increasingly acknowledged that immune cells depend on certain metabolic traits
to perform their functions and that the extracellular environment can influence cell …
to perform their functions and that the extracellular environment can influence cell …
Etomoxir actions on regulatory and memory T cells are independent of Cpt1a-mediated fatty acid oxidation
T cell subsets including effector (T eff), regulatory (T reg), and memory (T mem) cells are
characterized by distinct metabolic profiles that influence their differentiation and function …
characterized by distinct metabolic profiles that influence their differentiation and function …
Malonylation of GAPDH is an inflammatory signal in macrophages
S Galván-Peña, RG Carroll, C Newman… - Nature …, 2019 - nature.com
Macrophages undergo metabolic changes during activation that are coupled to functional
responses. The gram negative bacterial product lipopolysaccharide (LPS) is especially …
responses. The gram negative bacterial product lipopolysaccharide (LPS) is especially …
Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism
Acetyl-CoA carboxylase (ACC) regulates lipid synthesis; however, its role in inflammatory
regulation in macrophages remains unclear. We generated mice that are deficient in both …
regulation in macrophages remains unclear. We generated mice that are deficient in both …
[HTML][HTML] Macrophage metabolic reprogramming during chronic lung disease
Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …
What are the prospects for using complexes of copper (II) and zinc (II) to suppress the vital activity of Mycolicibacterium smegmatis?
IA Lutsenko, DE Baravikov, KA Koshenskova… - RSC …, 2022 - pubs.rsc.org
New complexes of zinc (II) and copper (II) with 2-furoic acid (Hfur), acetic acids and N-donor
ligands with the compositions [Zn2 (fur) 4] n (1),[Zn2 (fur) 4 (NH2py) 2](2, NH2py= 3 …
ligands with the compositions [Zn2 (fur) 4] n (1),[Zn2 (fur) 4 (NH2py) 2](2, NH2py= 3 …
Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts
CD 8+ T cells are key members of the adaptive immune response against infections and
cancer. As we discuss in this review, these cells can present diverse metabolic …
cancer. As we discuss in this review, these cells can present diverse metabolic …
Lipid metabolism: immune regulation and therapeutic prospectives in systemic lupus erythematosus
W Sun, P Li, J Cai, J Ma, X Zhang, Y Song… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a heterogeneous disease characterized by the
production of abnormal autoantibodies and immune complexes that can affect the organ and …
production of abnormal autoantibodies and immune complexes that can affect the organ and …
Exploring the role of ATP-citrate lyase in the immune system
M Dominguez, B Brüne, D Namgaladze - Frontiers in immunology, 2021 - frontiersin.org
Studies over the past decade have revealed that metabolism profoundly influences immune
responses. In particular, metabolism causes epigenetic regulation of gene expression, as a …
responses. In particular, metabolism causes epigenetic regulation of gene expression, as a …