Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial disease involving genetic and environmental factors, with …

Type 2 diabetes mellitus (T2DM) is common and increasing in prevalence worldwide, with
devastating public health consequences. While peripheral insulin resistance is a key feature …

Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

Alzheimer's disease (AD) is a progressive and degenerative disorder accompanied by
cognitive decline, which could be promoted by mitochondrial dysfunction induced by …

Alzheimer's disease (AD) is a progressive neurodegenerative illness responsible for
cognitive impairment and dementia. Accumulation of amyloid-beta (Aβ) peptides in neurons …

Background: Serum non-high-density lipoprotein-cholesterol (non-HDL-C) levels may be
associated with cognitive function. Objective: The objective of this study was to evaluate the …

One of the major obstacles confronting the formulation of a mechanistic understanding for
Alzheimer's disease (AD) is its immense complexity—a complexity that traverses the full …

Consumption of high-fat diets (HFD) is associated with brain alterations, including changes
in feeding behavior, cognitive decline, and dementia. Astrocytes play a role in HFD-induced …

Methods Depressive-like behaviors and cognitive decline in hTau mice were induced by
chronic restraint stress (CRS). Computational prediction and molecular experiments …

High-fat diet-induced metabolic changes are not restricted to the onset of cardiovascular
diseases, but also include effects on brain functions related to learning and memory. This …