[HTML][HTML] Effects of aging on the association between cerebrovascular responses to visual stimulation, hypercapnia and arterial stiffness

D Flück, AE Beaudin, CD Steinback… - Frontiers in …, 2014 - frontiersin.org
Aging is associated with decreased vascular compliance and diminished neurovascular-and
hypercapnia-evoked cerebral blood flow (CBF) responses. However, the interplay between …

Heterogeneous patterns of vasoreactivity in the middle cerebral and internal carotid arteries

NS Coverdale, S Lalande, A Perrotta… - American Journal of …, 2015 - journals.physiology.org
This study compared changes in cross-sectional area (CSA) and flow (Q) between the
middle cerebral artery (MCA) and the internal carotid artery (ICA) at baseline and during 5 …

[HTML][HTML] Cognitive function during exercise under severe hypoxia

T Komiyama, K Katayama, M Sudo, K Ishida… - Scientific Reports, 2017 - nature.com
Acute exercise has been demonstrated to improve cognitive function. In contrast, severe
hypoxia can impair cognitive function. Hence, cognitive function during exercise under …

Cerebral vascular control and metabolism in heat stress

AR Bain, L Nybo, PN Ainslie - Comprehensive Physiology, 2011 - Wiley Online Library
This review provides an in‐depth update on the impact of heat stress on cerebrovascular
functioning. The regulation of cerebral temperature, blood flow, and metabolism are …

[HTML][HTML] Contrasting measures of cerebrovascular reactivity between MRI and Doppler: a cross-sectional study of younger and older healthy individuals

CV Burley, ST Francis, KN Thomas… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) is used as an outcome measure of brain health.
Traditionally, lower CVR is associated with ageing, poor fitness and brain-related conditions …

Lifelong exposure to high‐altitude hypoxia in humans is associated with improved redox homeostasis and structural–functional adaptations of the neurovascular unit

BS Stacey, RL Hoiland, HG Caldwell… - The Journal of …, 2023 - Wiley Online Library
High‐altitude (HA) hypoxia may alter the structural–functional integrity of the neurovascular
unit (NVU). Herein, we compared male lowlanders (n= 9) at sea level (SL) and after 14 days …

Regional changes in brain blood flow during severe passive hyperthermia: effects of PaCO2 and extracranial blood flow

AR Bain, KJ Smith, NC Lewis… - Journal of Applied …, 2013 - journals.physiology.org
We investigated 1) the regional distribution of cerebral blood flow (CBF), 2) the influence of
end-tidal Pco2 (PetCO2) on CBF, and 3) the potential for an extracranial blood “steal” from …

Impact of transient hypotension on regional cerebral blood flow in humans

NCS Lewis, KJ Smith, AR Bain, KW Wildfong… - Clinical …, 2015 - portlandpress.com
We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …

Effect of acute hypoxia on blood flow in vertebral and internal carotid arteries

S Ogoh, K Sato, H Nakahara, K Okazaki… - Experimental …, 2013 - Wiley Online Library
New Findings• What is the central question of this study? Does hypoxia enhance blood flow
to all parts of the brain uniformly?• What is the main finding and its importance? During …

Recent insights into mechanisms of hypoxia‐induced vasodilatation in the human brain

JMJR Carr, RL Hoiland, IA Fernandes… - The Journal of …, 2023 - Wiley Online Library
The cerebral vasculature manages oxygen delivery by adjusting arterial blood in‐flow in the
face of reductions in oxygen availability. Hypoxic cerebral vasodilatation, and the associated …