Classification of leprosy into multibacillary and paucibacillary groups: an analysis

O Parkash - FEMS Immunology & Medical Microbiology, 2009 - academic.oup.com
Classification of leprosy patients into multibacillary and paucibacillary determines the
duration of their treatment. Misclassification leads to increased risk of relapse due to …

Rapid quantitative serological test for detection of infection with Mycobacterium leprae, the causative agent of leprosy

MS Duthie, MF Balagon, A Maghanoy… - Journal of clinical …, 2014 - Am Soc Microbiol
Leprosy remains an important health problem in a number of regions. Early detection of
infection, followed by effective treatment, is critical to reduce disease progression. New …

A quantitative view on Mycobacterium leprae antigens by proteomics

HG Wiker, GG Tomazella, GA De Souza - Journal of proteomics, 2011 - Elsevier
Leprosy is an ancient disease and the focus of the researchers' scrutiny for more than a
century. However, many of the molecular aspects related to transmission, virulence …

Performance of recombinant ESAT‐6 antigen (ML0049) for detection of leprosy patients

O Parkash, R Pandey, A Kumar… - Letters in applied …, 2007 - academic.oup.com
Aims: The study was aimed to evaluate the Mycobacterium leprae recombinant early
secreted antigenic target‐6 (rESAT‐6) for its serological performance in leprosy patients …

Advances in Proteomics of Mycobacterium leprae

O Parkash, BP Singh - Scandinavian Journal of Immunology, 2012 - Wiley Online Library
Although Mycobacterium leprae was the first bacterial pathogen identified causing human
disease, it remains one of the few that is non‐cultivable. Understanding the biology of M …

Serological detection of leprosy employing Mycobacterium leprae derived serine-rich 45 kDa, ESAT-6, CFP-10 and PGL-I: a compilation of data from studies in Indian …

O Parkash - Leprosy review, 2011 - leprosyreview.org
This article is a compilation of our findings recorded in the recent past where we have
investigated the serological performance of Mycobacterium leprae antigens like-serine-rich …

[HTML][HTML] Diagnostic accuracy of tests using recombinant protein antigens of Mycobacterium leprae for leprosy: A systematic review

ALG de Oliveira, VG Fraga… - Journal of infection and …, 2020 - Elsevier
The aim of this systematic review was to investigate the studies that evaluated the sensitivity
and specificity of serologic tests using recombinant protein antigens from Mycobacterium …

[HTML][HTML] Detection of serum antibodies to M. leprae Major Membrane Protein-II in leprosy patients from Indonesia

M Hatta, M Makino, M Sabir, N Tandirogang… - Leprosy …, 2009 - leprosyreview.org
Background Sero-diagnostic methods are the easiest way of diagnosing an infectious
disease in developing countries. In leprosy, phenolic glycolipid-1 (PGL-I) based methods for …

[PDF][PDF] Immunoproteomic analysis of Mycobacterium leprae derived cell membrane antigen

A Kumar, BK Girdhar, O Parkash - Int J Biol Med Res, 2010 - academia.edu
The aim of the study was serological characterization of antigens of cell membrane proteins
(MLMA) of armadillo derived Mycobacterium leprae, a causative organism of leprosy. Cell …

Serological heterogeneity against various Mycobacterium leprae antigens and its use in serodiagnosis of leprosy patients.

OP Om Parkash, AK Ajay Kumar, RP Richa Pandey… - 2007 - cabidigitallibrary.org
This study evaluated serological heterogeneity among assays used in serodiagnosis of
leprosy, including those based on PGL-I, 45 kDa antigen, ESAT-6 and CFP-10. Also, the …