Syncytiotrophoblast stress in preeclampsia: the convergence point for multiple pathways
CWG Redman, AC Staff, JM Roberts - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …
Pre-eclampsia: pathophysiology and clinical implications
GJ Burton, CW Redman, JM Roberts, A Moffett - Bmj, 2019 - bmj.com
Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …
presentation is highly variable but hypertension and proteinuria are usually seen. These …
Pathophysiology of placental-derived fetal growth restriction
GJ Burton, E Jauniaux - American journal of obstetrics and gynecology, 2018 - Elsevier
Placental-related fetal growth restriction arises primarily due to deficient remodeling of the
uterine spiral arteries supplying the placenta during early pregnancy. The resultant …
uterine spiral arteries supplying the placenta during early pregnancy. The resultant …
[HTML][HTML] Oxidative stress: Normal pregnancy versus preeclampsia
DI Chiarello, C Abad, D Rojas, F Toledo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …
[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia
R Marín, DI Chiarello, C Abad, D Rojas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
Metabolic reprogramming by Zika virus provokes inflammation in human placenta
The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy
loss when maternal infection occurs in early pregnancy, but specific mechanisms driving …
loss when maternal infection occurs in early pregnancy, but specific mechanisms driving …
Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy
Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta
P Nogues, E Dos Santos, H Jammes, P Berveiller… - Clinical …, 2019 - Springer
Background It is well established that obesity is associated with dysregulation of the ratio
between the two major adipokines leptin and adiponectin. Furthermore, it was recently …
between the two major adipokines leptin and adiponectin. Furthermore, it was recently …